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SHIP1 Controls Internal Platelet Contraction and α(IIb)β(3) Integrin Dynamics in Early Platelet Activation
The Src homology 2 domain-containing inositol 5-phosphatase 1 (SHIP1) is known to dephosphorylate PtdIns(3,4,5)P(3) into PtdIns(3,4)P(2) and to interact with several signaling proteins though its docking functions. It has been shown to negatively regulate platelet adhesion and spreading on a fibrino...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860818/ https://www.ncbi.nlm.nih.gov/pubmed/36674478 http://dx.doi.org/10.3390/ijms24020958 |