Minibody-Based and scFv-Based Antibody Fragment-Drug Conjugates Selectively Eliminate GD2-Positive Tumor Cells

Ganglioside GD2 is a well-established target expressed on multiple solid tumors, many of which are characterized by low treatment efficiency. Antibody-drug conjugates (ADCs) have demonstrated marked success in a number of solid tumors, and GD2-directed drug conjugates may also hold strong therapeuti...

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Detalles Bibliográficos
Autores principales: Kalinovsky, Daniel V., Kholodenko, Irina V., Kibardin, Alexey V., Doronin, Igor I., Svirshchevskaya, Elena V., Ryazantsev, Dmitriy Y., Konovalova, Maria V., Rozov, Fedor N., Larin, Sergey S., Deyev, Sergey M., Kholodenko, Roman V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860947/
https://www.ncbi.nlm.nih.gov/pubmed/36674755
http://dx.doi.org/10.3390/ijms24021239

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