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Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting
Different E. coli pathotypes are common zoonotic agents. Some of these pathotypes cause recurrent and widespread calf diarrhea and contribute to significant economic losses in the livestock sector worldwide in addition to putting humans at risk. Here, we investigated the occurrence of E. coli pathot...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861035/ https://www.ncbi.nlm.nih.gov/pubmed/36678390 http://dx.doi.org/10.3390/pathogens12010042 |
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author | Chekole, Wagaw Sendeku Adamu, Haileeyesus Sternberg-Lewrein, Susanna Magnusson, Ulf Tessema, Tesfaye Sisay |
author_facet | Chekole, Wagaw Sendeku Adamu, Haileeyesus Sternberg-Lewrein, Susanna Magnusson, Ulf Tessema, Tesfaye Sisay |
author_sort | Chekole, Wagaw Sendeku |
collection | PubMed |
description | Different E. coli pathotypes are common zoonotic agents. Some of these pathotypes cause recurrent and widespread calf diarrhea and contribute to significant economic losses in the livestock sector worldwide in addition to putting humans at risk. Here, we investigated the occurrence of E. coli pathotypes in diarrheic calves in Ethiopia kept under various calf management practices. One hundred fecal samples were collected from diarrheic calves in 98 different farms. E. coli was isolated in the samples from 99 of the diarrheic calves, and virulence genes were detected in 80% of the samples. The occurrence of E. coli pathotypes in the samples was 32% ETEC, 23% STEC, 18% STEC/ETEC, 3% EPEC, 2% EAEC, and 1% EHEC. No diarrheic calves were positive for the EIEC and DAEC pathotypes. The occurrence of pathotypes was positively associated with female calves (EPEC, p = 0.006), aged less than 2 weeks (STEC, p = 0.059), and calves fed colostrum via the hand method (STEC, p = 0.008 and EAEC, p = 0.003). This study revealed that several E. coli pathotypes occurred among calves affected with diarrhea. Moreover, the presence of a mixed STEC/ETEC pathotypes infection was present in the studied low-income setting. These findings indicate a considerable risk for the zoonotic transmission from calves to humans and the options to provide the better management for younger calves in order to reduce the economic loss. |
format | Online Article Text |
id | pubmed-9861035 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98610352023-01-22 Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting Chekole, Wagaw Sendeku Adamu, Haileeyesus Sternberg-Lewrein, Susanna Magnusson, Ulf Tessema, Tesfaye Sisay Pathogens Article Different E. coli pathotypes are common zoonotic agents. Some of these pathotypes cause recurrent and widespread calf diarrhea and contribute to significant economic losses in the livestock sector worldwide in addition to putting humans at risk. Here, we investigated the occurrence of E. coli pathotypes in diarrheic calves in Ethiopia kept under various calf management practices. One hundred fecal samples were collected from diarrheic calves in 98 different farms. E. coli was isolated in the samples from 99 of the diarrheic calves, and virulence genes were detected in 80% of the samples. The occurrence of E. coli pathotypes in the samples was 32% ETEC, 23% STEC, 18% STEC/ETEC, 3% EPEC, 2% EAEC, and 1% EHEC. No diarrheic calves were positive for the EIEC and DAEC pathotypes. The occurrence of pathotypes was positively associated with female calves (EPEC, p = 0.006), aged less than 2 weeks (STEC, p = 0.059), and calves fed colostrum via the hand method (STEC, p = 0.008 and EAEC, p = 0.003). This study revealed that several E. coli pathotypes occurred among calves affected with diarrhea. Moreover, the presence of a mixed STEC/ETEC pathotypes infection was present in the studied low-income setting. These findings indicate a considerable risk for the zoonotic transmission from calves to humans and the options to provide the better management for younger calves in order to reduce the economic loss. MDPI 2022-12-27 /pmc/articles/PMC9861035/ /pubmed/36678390 http://dx.doi.org/10.3390/pathogens12010042 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chekole, Wagaw Sendeku Adamu, Haileeyesus Sternberg-Lewrein, Susanna Magnusson, Ulf Tessema, Tesfaye Sisay Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting |
title | Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting |
title_full | Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting |
title_fullStr | Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting |
title_full_unstemmed | Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting |
title_short | Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting |
title_sort | occurrence of escherichia coli pathotypes in diarrheic calves in a low-income setting |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861035/ https://www.ncbi.nlm.nih.gov/pubmed/36678390 http://dx.doi.org/10.3390/pathogens12010042 |
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