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Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting

Different E. coli pathotypes are common zoonotic agents. Some of these pathotypes cause recurrent and widespread calf diarrhea and contribute to significant economic losses in the livestock sector worldwide in addition to putting humans at risk. Here, we investigated the occurrence of E. coli pathot...

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Autores principales: Chekole, Wagaw Sendeku, Adamu, Haileeyesus, Sternberg-Lewrein, Susanna, Magnusson, Ulf, Tessema, Tesfaye Sisay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861035/
https://www.ncbi.nlm.nih.gov/pubmed/36678390
http://dx.doi.org/10.3390/pathogens12010042
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author Chekole, Wagaw Sendeku
Adamu, Haileeyesus
Sternberg-Lewrein, Susanna
Magnusson, Ulf
Tessema, Tesfaye Sisay
author_facet Chekole, Wagaw Sendeku
Adamu, Haileeyesus
Sternberg-Lewrein, Susanna
Magnusson, Ulf
Tessema, Tesfaye Sisay
author_sort Chekole, Wagaw Sendeku
collection PubMed
description Different E. coli pathotypes are common zoonotic agents. Some of these pathotypes cause recurrent and widespread calf diarrhea and contribute to significant economic losses in the livestock sector worldwide in addition to putting humans at risk. Here, we investigated the occurrence of E. coli pathotypes in diarrheic calves in Ethiopia kept under various calf management practices. One hundred fecal samples were collected from diarrheic calves in 98 different farms. E. coli was isolated in the samples from 99 of the diarrheic calves, and virulence genes were detected in 80% of the samples. The occurrence of E. coli pathotypes in the samples was 32% ETEC, 23% STEC, 18% STEC/ETEC, 3% EPEC, 2% EAEC, and 1% EHEC. No diarrheic calves were positive for the EIEC and DAEC pathotypes. The occurrence of pathotypes was positively associated with female calves (EPEC, p = 0.006), aged less than 2 weeks (STEC, p = 0.059), and calves fed colostrum via the hand method (STEC, p = 0.008 and EAEC, p = 0.003). This study revealed that several E. coli pathotypes occurred among calves affected with diarrhea. Moreover, the presence of a mixed STEC/ETEC pathotypes infection was present in the studied low-income setting. These findings indicate a considerable risk for the zoonotic transmission from calves to humans and the options to provide the better management for younger calves in order to reduce the economic loss.
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spelling pubmed-98610352023-01-22 Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting Chekole, Wagaw Sendeku Adamu, Haileeyesus Sternberg-Lewrein, Susanna Magnusson, Ulf Tessema, Tesfaye Sisay Pathogens Article Different E. coli pathotypes are common zoonotic agents. Some of these pathotypes cause recurrent and widespread calf diarrhea and contribute to significant economic losses in the livestock sector worldwide in addition to putting humans at risk. Here, we investigated the occurrence of E. coli pathotypes in diarrheic calves in Ethiopia kept under various calf management practices. One hundred fecal samples were collected from diarrheic calves in 98 different farms. E. coli was isolated in the samples from 99 of the diarrheic calves, and virulence genes were detected in 80% of the samples. The occurrence of E. coli pathotypes in the samples was 32% ETEC, 23% STEC, 18% STEC/ETEC, 3% EPEC, 2% EAEC, and 1% EHEC. No diarrheic calves were positive for the EIEC and DAEC pathotypes. The occurrence of pathotypes was positively associated with female calves (EPEC, p = 0.006), aged less than 2 weeks (STEC, p = 0.059), and calves fed colostrum via the hand method (STEC, p = 0.008 and EAEC, p = 0.003). This study revealed that several E. coli pathotypes occurred among calves affected with diarrhea. Moreover, the presence of a mixed STEC/ETEC pathotypes infection was present in the studied low-income setting. These findings indicate a considerable risk for the zoonotic transmission from calves to humans and the options to provide the better management for younger calves in order to reduce the economic loss. MDPI 2022-12-27 /pmc/articles/PMC9861035/ /pubmed/36678390 http://dx.doi.org/10.3390/pathogens12010042 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chekole, Wagaw Sendeku
Adamu, Haileeyesus
Sternberg-Lewrein, Susanna
Magnusson, Ulf
Tessema, Tesfaye Sisay
Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting
title Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting
title_full Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting
title_fullStr Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting
title_full_unstemmed Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting
title_short Occurrence of Escherichia coli Pathotypes in Diarrheic Calves in a Low-Income Setting
title_sort occurrence of escherichia coli pathotypes in diarrheic calves in a low-income setting
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861035/
https://www.ncbi.nlm.nih.gov/pubmed/36678390
http://dx.doi.org/10.3390/pathogens12010042
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