Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV—Based Vectors and for a Cure for HIV-1 Infection

To complete their replication cycle, retroviruses need to integrate a DNA copy of their RNA genome into a host chromosome. Integration site selection is not random and is driven by multiple viral and cellular host factors specific to different classes of retroviruses. Today, overwhelming evidence fr...

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Detalles Bibliográficos
Autores principales: Pellaers, Eline, Bhat, Anayat, Christ, Frauke, Debyser, Zeger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861059/
https://www.ncbi.nlm.nih.gov/pubmed/36680071
http://dx.doi.org/10.3390/v15010032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861059/
https://www.ncbi.nlm.nih.gov/pubmed/36680071
http://dx.doi.org/10.3390/v15010032

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