Recombinant Human Clusterin Seals Damage to the Ocular Surface Barrier in a Mouse Model of Ophthalmic Preservative-Induced Epitheliopathy

There is a significant unmet need for therapeutics to treat ocular surface barrier damage, also called epitheliopathy, due to dry eye and related diseases. We recently reported that the natural tear glycoprotein CLU (clusterin), a molecular chaperone and matrix metalloproteinase inhibitor, seals and...

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Detalles Bibliográficos
Autores principales: Chintala, Shravan K., Pan, Jinhong, Satapathy, Sandeep, Condruti, Rebecca, Hao, Zixuan, Liu, Pei-wen, O’Conner, Christian F., Barr, Joseph T., Wilson, Mark R., Jeong, Shinwu, Fini, M. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861099/
https://www.ncbi.nlm.nih.gov/pubmed/36674497
http://dx.doi.org/10.3390/ijms24020981

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