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KRAS Mutations in Solid Tumors: Characteristics, Current Therapeutic Strategy, and Potential Treatment Exploration

Kristen rat sarcoma (KRAS) gene is one of the most common mutated oncogenes in solid tumors. Yet, KRAS inhibitors did not follow suit with the development of targeted therapy, for the structure of KRAS has been considered as being implausible to target for decades. Chemotherapy was the initial recom...

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Detalles Bibliográficos
Autores principales: Yang, Yunkai, Zhang, Huan, Huang, Shanshan, Chu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861148/
https://www.ncbi.nlm.nih.gov/pubmed/36675641
http://dx.doi.org/10.3390/jcm12020709

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