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A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection

Radiotherapy is now recognized as a pillar in the fight against cancer. Two different types are currently used in clinical practice: (1) external beam radiotherapy, using high-energy X-rays or electron beams, both in the MeV-range, and (2) intraoperative radiotherapy, using low-energy X-rays (up to...

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Autores principales: Pettinato, Sara, Girolami, Marco, Stravato, Antonella, Serpente, Valerio, Musio, Daniela, Rossi, Maria C., Trucchi, Daniele M., Olivieri, Riccardo, Salvatori, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861322/
https://www.ncbi.nlm.nih.gov/pubmed/36676560
http://dx.doi.org/10.3390/ma16020824
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author Pettinato, Sara
Girolami, Marco
Stravato, Antonella
Serpente, Valerio
Musio, Daniela
Rossi, Maria C.
Trucchi, Daniele M.
Olivieri, Riccardo
Salvatori, Stefano
author_facet Pettinato, Sara
Girolami, Marco
Stravato, Antonella
Serpente, Valerio
Musio, Daniela
Rossi, Maria C.
Trucchi, Daniele M.
Olivieri, Riccardo
Salvatori, Stefano
author_sort Pettinato, Sara
collection PubMed
description Radiotherapy is now recognized as a pillar in the fight against cancer. Two different types are currently used in clinical practice: (1) external beam radiotherapy, using high-energy X-rays or electron beams, both in the MeV-range, and (2) intraoperative radiotherapy, using low-energy X-rays (up to 50 keV) and MeV-range electron beams. Versatile detectors able to measure the radiation dose independently from the radiation nature and energy are therefore extremely appealing to medical physicists. In this work, a dosimeter based on a high-quality single-crystal synthetic diamond sample was designed, fabricated and characterized under low-energy X-rays, as well as under high-energy pulsed X-rays and electron beams, demonstrating excellent linearity with radiation dose and dose-rate. Detector sensitivity was measured to be 0.299 ± 0.002 µC/Gy under 6 MeV X-ray photons, and 0.298 ± 0.004 µC/Gy under 6 MeV electrons, highlighting that the response of the diamond dosimeter is independent of the radiation nature. Moreover, in the case of low-energy X-rays, an extremely low limit of detection (23 nGy/s) was evaluated, pointing out the suitability of the device to radiation protection dosimetry.
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spelling pubmed-98613222023-01-22 A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection Pettinato, Sara Girolami, Marco Stravato, Antonella Serpente, Valerio Musio, Daniela Rossi, Maria C. Trucchi, Daniele M. Olivieri, Riccardo Salvatori, Stefano Materials (Basel) Article Radiotherapy is now recognized as a pillar in the fight against cancer. Two different types are currently used in clinical practice: (1) external beam radiotherapy, using high-energy X-rays or electron beams, both in the MeV-range, and (2) intraoperative radiotherapy, using low-energy X-rays (up to 50 keV) and MeV-range electron beams. Versatile detectors able to measure the radiation dose independently from the radiation nature and energy are therefore extremely appealing to medical physicists. In this work, a dosimeter based on a high-quality single-crystal synthetic diamond sample was designed, fabricated and characterized under low-energy X-rays, as well as under high-energy pulsed X-rays and electron beams, demonstrating excellent linearity with radiation dose and dose-rate. Detector sensitivity was measured to be 0.299 ± 0.002 µC/Gy under 6 MeV X-ray photons, and 0.298 ± 0.004 µC/Gy under 6 MeV electrons, highlighting that the response of the diamond dosimeter is independent of the radiation nature. Moreover, in the case of low-energy X-rays, an extremely low limit of detection (23 nGy/s) was evaluated, pointing out the suitability of the device to radiation protection dosimetry. MDPI 2023-01-14 /pmc/articles/PMC9861322/ /pubmed/36676560 http://dx.doi.org/10.3390/ma16020824 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pettinato, Sara
Girolami, Marco
Stravato, Antonella
Serpente, Valerio
Musio, Daniela
Rossi, Maria C.
Trucchi, Daniele M.
Olivieri, Riccardo
Salvatori, Stefano
A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection
title A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection
title_full A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection
title_fullStr A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection
title_full_unstemmed A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection
title_short A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection
title_sort highly versatile x-ray and electron beam diamond dosimeter for radiation therapy and protection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861322/
https://www.ncbi.nlm.nih.gov/pubmed/36676560
http://dx.doi.org/10.3390/ma16020824
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