Cargando…
Discovery of Tryptanthrin and Its Derivatives and Its Activities against NSCLC In Vitro via Both Apoptosis and Autophagy Pathways
In this study, a series of novel tryptanthrin derivatives were synthesized and their inhibitory activities against selected human cancer cell lines, namely, lung (A549), chronic myeloid leukemia (K562), prostate (PC3), and live (HepG2), were evaluated using a methyl thiazolyl tetrazolium colorimetri...
Autores principales: | Zou, Yayu, Zhang, Guanglong, Li, Chengpeng, Long, Haitao, Chen, Danping, Li, Zhurui, Ouyang, Guiping, Zhang, Wenjing, Zhang, Yi, Wang, Zhenchao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861433/ https://www.ncbi.nlm.nih.gov/pubmed/36674964 http://dx.doi.org/10.3390/ijms24021450 |
Ejemplares similares
-
Discovery and Mechanism of Novel 7-Aliphatic Amine Tryptanthrin Derivatives against Phytopathogenic Bacteria
por: Long, Xuesha, et al.
Publicado: (2023) -
Synthesis and biological assessment of indole derivatives containing penta-heterocycles scaffold as novel anticancer agents towards A549 and K562 cells
por: Zhang, Guanglong, et al.
Publicado: (2023) -
Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis
por: Kirpotina, Liliya N., et al.
Publicado: (2020) -
Discovery of Novel Tryptanthrin Derivatives with Benzenesulfonamide Substituents as Multi-Target-Directed Ligands for the Treatment of Alzheimer’s Disease
por: Wang, Guoxing, et al.
Publicado: (2023) -
Synthesis and evaluation of the antiplasmodial activity of tryptanthrin derivatives
por: Onambele, Liliane Abodo, et al.
Publicado: (2015)