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Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications

In the present scenario, the research is now being focused on the naturally occurring polymers that can gradually replace the existing synthetic polymers for the development of bio composites having applications in medical surgeries and human implants. With promising mechanical properties and bio co...

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Autores principales: Ranakoti, Lalit, Gangil, Brijesh, Bhandari, Prabhakar, Singh, Tej, Sharma, Shubham, Singh, Jujhar, Singh, Sunpreet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861437/
https://www.ncbi.nlm.nih.gov/pubmed/36677545
http://dx.doi.org/10.3390/molecules28020485
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author Ranakoti, Lalit
Gangil, Brijesh
Bhandari, Prabhakar
Singh, Tej
Sharma, Shubham
Singh, Jujhar
Singh, Sunpreet
author_facet Ranakoti, Lalit
Gangil, Brijesh
Bhandari, Prabhakar
Singh, Tej
Sharma, Shubham
Singh, Jujhar
Singh, Sunpreet
author_sort Ranakoti, Lalit
collection PubMed
description In the present scenario, the research is now being focused on the naturally occurring polymers that can gradually replace the existing synthetic polymers for the development of bio composites having applications in medical surgeries and human implants. With promising mechanical properties and bio compatibility with human tissues, poly lactic acid (PLA) is now being viewed as a future bio material. In order to examine the applicability of PLA in human implants, the current article sheds light on the synthesis of PLA and its various copolymers used to alter its physical and mechanical properties. In the latter half, various processes used for the fabrication of biomaterials are discussed in detail. Finally, biomaterials that are currently in use in the field of biomedical (Scaffolding, drug delivery, tissue engineering, medical implants, derma, cosmetics, medical surgeries, and human implants) are represented with respective advantages in the sphere of biomaterials.
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spelling pubmed-98614372023-01-22 Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications Ranakoti, Lalit Gangil, Brijesh Bhandari, Prabhakar Singh, Tej Sharma, Shubham Singh, Jujhar Singh, Sunpreet Molecules Review In the present scenario, the research is now being focused on the naturally occurring polymers that can gradually replace the existing synthetic polymers for the development of bio composites having applications in medical surgeries and human implants. With promising mechanical properties and bio compatibility with human tissues, poly lactic acid (PLA) is now being viewed as a future bio material. In order to examine the applicability of PLA in human implants, the current article sheds light on the synthesis of PLA and its various copolymers used to alter its physical and mechanical properties. In the latter half, various processes used for the fabrication of biomaterials are discussed in detail. Finally, biomaterials that are currently in use in the field of biomedical (Scaffolding, drug delivery, tissue engineering, medical implants, derma, cosmetics, medical surgeries, and human implants) are represented with respective advantages in the sphere of biomaterials. MDPI 2023-01-04 /pmc/articles/PMC9861437/ /pubmed/36677545 http://dx.doi.org/10.3390/molecules28020485 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ranakoti, Lalit
Gangil, Brijesh
Bhandari, Prabhakar
Singh, Tej
Sharma, Shubham
Singh, Jujhar
Singh, Sunpreet
Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications
title Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications
title_full Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications
title_fullStr Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications
title_full_unstemmed Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications
title_short Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications
title_sort promising role of polylactic acid as an ingenious biomaterial in scaffolds, drug delivery, tissue engineering, and medical implants: research developments, and prospective applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861437/
https://www.ncbi.nlm.nih.gov/pubmed/36677545
http://dx.doi.org/10.3390/molecules28020485
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