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The Solubility Studies and the Complexation Mechanism Investigations of Biologically Active Spiro[cyclopropane-1,3′-oxindoles] with β-Cyclodextrins

In this work, we first improved the aqueous solubility of biologically active spiro[cyclopropane-1,3′-oxindoles] (SCOs) via their complexation with different β-cyclodextrins (β-CDs) and proposed a possible mechanism of the complex formation. β-CDs significantly increased the water solubility of SCOs...

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Detalles Bibliográficos
Autores principales:	Kravtsova, Anna A., Skuredina, Anna A., Malyshev, Alexander S., Le-Deygen, Irina M., Kudryashova, Elena V., Budynina, Ekaterina M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861668/ https://www.ncbi.nlm.nih.gov/pubmed/36678857 http://dx.doi.org/10.3390/pharmaceutics15010228

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