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Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study

There is a significant change in the bacterial plaque populations in the oral cavity during and after orthodontic treatment. Numerous studies have demonstrated that 2–96% of patients could increase the risk of white spot lesions. Streptococcus mutans and Lactobacilli ssp. are responsible for these w...

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Autores principales: Tristán-López, Jesús-David, Niño-Martínez, Nereyda, Kolosovas-Machuca, Eleazar-Samuel, Patiño-Marín, Nuria, De Alba-Montero, Idania, Bach, Horacio, Martínez-Castañón, Gabriel-Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861692/
https://www.ncbi.nlm.nih.gov/pubmed/36674917
http://dx.doi.org/10.3390/ijms24021401
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author Tristán-López, Jesús-David
Niño-Martínez, Nereyda
Kolosovas-Machuca, Eleazar-Samuel
Patiño-Marín, Nuria
De Alba-Montero, Idania
Bach, Horacio
Martínez-Castañón, Gabriel-Alejandro
author_facet Tristán-López, Jesús-David
Niño-Martínez, Nereyda
Kolosovas-Machuca, Eleazar-Samuel
Patiño-Marín, Nuria
De Alba-Montero, Idania
Bach, Horacio
Martínez-Castañón, Gabriel-Alejandro
author_sort Tristán-López, Jesús-David
collection PubMed
description There is a significant change in the bacterial plaque populations in the oral cavity during and after orthodontic treatment. Numerous studies have demonstrated that 2–96% of patients could increase the risk of white spot lesions. Streptococcus mutans and Lactobacilli ssp. are responsible for these white spot lesions. In this work, silver nanoparticles (AgNPs) with a diameter of 11 nm and dispersed in water were impregnated onto three different commercial orthodontic adhesives at 535 μg/mL. The shear bond strength (SBS) was assessed on 180 human premolars and metallic brackets. The premolars were divided into six groups (three groups for the commercial adhesives and three groups for the adhesives with AgNPs). All the groups were tested for their bactericidal properties, and their MIC, MBC, and agar template diffusion assays were measured. After adding AgNPs, the SBS was not significantly modified for any adhesive (p > 0.05), and the forces measured during the SBS did not exceed the threshold of 6 to 8 MPa for clinical acceptability in all groups. An increase in the bactericidal properties against both S. mutans and L. acidophilus was measured when the adhesives were supplemented with AgNPs. It was concluded that AgNPs can be supplement commercial orthodontic adhesives without modifying their mechanical properties with improved bactericidal activity.
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spelling pubmed-98616922023-01-22 Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study Tristán-López, Jesús-David Niño-Martínez, Nereyda Kolosovas-Machuca, Eleazar-Samuel Patiño-Marín, Nuria De Alba-Montero, Idania Bach, Horacio Martínez-Castañón, Gabriel-Alejandro Int J Mol Sci Article There is a significant change in the bacterial plaque populations in the oral cavity during and after orthodontic treatment. Numerous studies have demonstrated that 2–96% of patients could increase the risk of white spot lesions. Streptococcus mutans and Lactobacilli ssp. are responsible for these white spot lesions. In this work, silver nanoparticles (AgNPs) with a diameter of 11 nm and dispersed in water were impregnated onto three different commercial orthodontic adhesives at 535 μg/mL. The shear bond strength (SBS) was assessed on 180 human premolars and metallic brackets. The premolars were divided into six groups (three groups for the commercial adhesives and three groups for the adhesives with AgNPs). All the groups were tested for their bactericidal properties, and their MIC, MBC, and agar template diffusion assays were measured. After adding AgNPs, the SBS was not significantly modified for any adhesive (p > 0.05), and the forces measured during the SBS did not exceed the threshold of 6 to 8 MPa for clinical acceptability in all groups. An increase in the bactericidal properties against both S. mutans and L. acidophilus was measured when the adhesives were supplemented with AgNPs. It was concluded that AgNPs can be supplement commercial orthodontic adhesives without modifying their mechanical properties with improved bactericidal activity. MDPI 2023-01-11 /pmc/articles/PMC9861692/ /pubmed/36674917 http://dx.doi.org/10.3390/ijms24021401 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tristán-López, Jesús-David
Niño-Martínez, Nereyda
Kolosovas-Machuca, Eleazar-Samuel
Patiño-Marín, Nuria
De Alba-Montero, Idania
Bach, Horacio
Martínez-Castañón, Gabriel-Alejandro
Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study
title Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study
title_full Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study
title_fullStr Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study
title_full_unstemmed Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study
title_short Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study
title_sort application of silver nanoparticles to improve the antibacterial activity of orthodontic adhesives: an in vitro study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861692/
https://www.ncbi.nlm.nih.gov/pubmed/36674917
http://dx.doi.org/10.3390/ijms24021401
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