Cargando…
Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry
Background. Data on leadless pacemaker (LPM) implantation in an emergency setting are currently lacking. Objective. We aimed to investigate the feasibility of LPM implantation for emergency bradyarrhythmia, in patients referred for urgent PM implantation, in a large, multicenter, real-world cohort o...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861740/ https://www.ncbi.nlm.nih.gov/pubmed/36676690 http://dx.doi.org/10.3390/medicina59010067 |
_version_ | 1784874917404082176 |
---|---|
author | Schiavone, Marco Filtz, Annalisa Gasperetti, Alessio Breitenstein, Alexander Palmisano, Pietro Mitacchione, Gianfranco Gulletta, Simone Chierchia, Gian Battista Montemerlo, Elisabetta Statuto, Giovanni Russo, Giulia Casella, Michela Vitali, Francesco Mazzone, Patrizio Hofer, Daniel Arabia, Gianmarco Tundo, Fabrizio Ruggiero, Diego Fierro, Nicolai Moltrasio, Massimo Bertini, Matteo Dello Russo, Antonio Pisanò, Ennio C. L. Della Bella, Paolo Rovaris, Giovanni de Asmundis, Carlo Biffi, Mauro Curnis, Antonio Tondo, Claudio Saguner, Ardan M. Forleo, Giovanni B. |
author_facet | Schiavone, Marco Filtz, Annalisa Gasperetti, Alessio Breitenstein, Alexander Palmisano, Pietro Mitacchione, Gianfranco Gulletta, Simone Chierchia, Gian Battista Montemerlo, Elisabetta Statuto, Giovanni Russo, Giulia Casella, Michela Vitali, Francesco Mazzone, Patrizio Hofer, Daniel Arabia, Gianmarco Tundo, Fabrizio Ruggiero, Diego Fierro, Nicolai Moltrasio, Massimo Bertini, Matteo Dello Russo, Antonio Pisanò, Ennio C. L. Della Bella, Paolo Rovaris, Giovanni de Asmundis, Carlo Biffi, Mauro Curnis, Antonio Tondo, Claudio Saguner, Ardan M. Forleo, Giovanni B. |
author_sort | Schiavone, Marco |
collection | PubMed |
description | Background. Data on leadless pacemaker (LPM) implantation in an emergency setting are currently lacking. Objective. We aimed to investigate the feasibility of LPM implantation for emergency bradyarrhythmia, in patients referred for urgent PM implantation, in a large, multicenter, real-world cohort of LPM recipients. Methods. Two cohorts of LPM patients, stratified according to the LPM implantation scenario (patients admitted from the emergency department (ED+) vs. elective patients (ED−)) were retrieved from the iLEAPER registry. The primary outcome of the study was a comparison of the peri-procedural complications between the groups. The rates of peri-procedural characteristics (overall procedural and fluoroscopic duration) were deemed secondary outcomes. Results. A total of 1154 patients were enrolled in this project, with patients implanted due to an urgent bradyarrhythmia (ED+) representing 6.2% of the entire cohort. Slow atrial fibrillation and complete + advanced atrioventricular blocks were more frequent in the ED+ cohort (76.3% for ED+ vs. 49.7% for ED−, p = 0.025; 37.5% vs. 27.3%, p = 0.027, respectively). The overall procedural times were longer in the ED+ cohort (60 (45–80) mins vs. 50 (40–65) mins, p < 0.001), showing higher rates of temporary pacing (94.4% for ED+ vs. 28.9% for ED−, p < 0.001). Emergency LPM implantation was not correlated with an increase in the rate of major complications compared to the control group (6.9% ED+ vs. 4.2% ED−, p = 0.244). Conclusion. LPM implantation is a feasible procedure for the treatment of severe bradyarrhythmia in an urgent setting. Urgent LPM implantation was not correlated with an increase in the rate of major complications compared to the control group, but it was associated with longer procedural times. |
format | Online Article Text |
id | pubmed-9861740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98617402023-01-22 Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry Schiavone, Marco Filtz, Annalisa Gasperetti, Alessio Breitenstein, Alexander Palmisano, Pietro Mitacchione, Gianfranco Gulletta, Simone Chierchia, Gian Battista Montemerlo, Elisabetta Statuto, Giovanni Russo, Giulia Casella, Michela Vitali, Francesco Mazzone, Patrizio Hofer, Daniel Arabia, Gianmarco Tundo, Fabrizio Ruggiero, Diego Fierro, Nicolai Moltrasio, Massimo Bertini, Matteo Dello Russo, Antonio Pisanò, Ennio C. L. Della Bella, Paolo Rovaris, Giovanni de Asmundis, Carlo Biffi, Mauro Curnis, Antonio Tondo, Claudio Saguner, Ardan M. Forleo, Giovanni B. Medicina (Kaunas) Article Background. Data on leadless pacemaker (LPM) implantation in an emergency setting are currently lacking. Objective. We aimed to investigate the feasibility of LPM implantation for emergency bradyarrhythmia, in patients referred for urgent PM implantation, in a large, multicenter, real-world cohort of LPM recipients. Methods. Two cohorts of LPM patients, stratified according to the LPM implantation scenario (patients admitted from the emergency department (ED+) vs. elective patients (ED−)) were retrieved from the iLEAPER registry. The primary outcome of the study was a comparison of the peri-procedural complications between the groups. The rates of peri-procedural characteristics (overall procedural and fluoroscopic duration) were deemed secondary outcomes. Results. A total of 1154 patients were enrolled in this project, with patients implanted due to an urgent bradyarrhythmia (ED+) representing 6.2% of the entire cohort. Slow atrial fibrillation and complete + advanced atrioventricular blocks were more frequent in the ED+ cohort (76.3% for ED+ vs. 49.7% for ED−, p = 0.025; 37.5% vs. 27.3%, p = 0.027, respectively). The overall procedural times were longer in the ED+ cohort (60 (45–80) mins vs. 50 (40–65) mins, p < 0.001), showing higher rates of temporary pacing (94.4% for ED+ vs. 28.9% for ED−, p < 0.001). Emergency LPM implantation was not correlated with an increase in the rate of major complications compared to the control group (6.9% ED+ vs. 4.2% ED−, p = 0.244). Conclusion. LPM implantation is a feasible procedure for the treatment of severe bradyarrhythmia in an urgent setting. Urgent LPM implantation was not correlated with an increase in the rate of major complications compared to the control group, but it was associated with longer procedural times. MDPI 2022-12-28 /pmc/articles/PMC9861740/ /pubmed/36676690 http://dx.doi.org/10.3390/medicina59010067 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Schiavone, Marco Filtz, Annalisa Gasperetti, Alessio Breitenstein, Alexander Palmisano, Pietro Mitacchione, Gianfranco Gulletta, Simone Chierchia, Gian Battista Montemerlo, Elisabetta Statuto, Giovanni Russo, Giulia Casella, Michela Vitali, Francesco Mazzone, Patrizio Hofer, Daniel Arabia, Gianmarco Tundo, Fabrizio Ruggiero, Diego Fierro, Nicolai Moltrasio, Massimo Bertini, Matteo Dello Russo, Antonio Pisanò, Ennio C. L. Della Bella, Paolo Rovaris, Giovanni de Asmundis, Carlo Biffi, Mauro Curnis, Antonio Tondo, Claudio Saguner, Ardan M. Forleo, Giovanni B. Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry |
title | Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry |
title_full | Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry |
title_fullStr | Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry |
title_full_unstemmed | Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry |
title_short | Leadless Pacemaker Implantation in the Emergency Bradyarrhythmia Setting: Results from a Multicenter European Registry |
title_sort | leadless pacemaker implantation in the emergency bradyarrhythmia setting: results from a multicenter european registry |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861740/ https://www.ncbi.nlm.nih.gov/pubmed/36676690 http://dx.doi.org/10.3390/medicina59010067 |
work_keys_str_mv | AT schiavonemarco leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT filtzannalisa leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT gasperettialessio leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT breitensteinalexander leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT palmisanopietro leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT mitacchionegianfranco leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT gullettasimone leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT chierchiagianbattista leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT montemerloelisabetta leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT statutogiovanni leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT russogiulia leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT casellamichela leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT vitalifrancesco leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT mazzonepatrizio leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT hoferdaniel leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT arabiagianmarco leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT tundofabrizio leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT ruggierodiego leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT fierronicolai leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT moltrasiomassimo leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT bertinimatteo leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT dellorussoantonio leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT pisanoenniocl leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT dellabellapaolo leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT rovarisgiovanni leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT deasmundiscarlo leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT biffimauro leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT curnisantonio leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT tondoclaudio leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT sagunerardanm leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry AT forleogiovannib leadlesspacemakerimplantationintheemergencybradyarrhythmiasettingresultsfromamulticentereuropeanregistry |