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A Promising Biomolecule Able to Degrade Neutrophil Extracellular Traps: CdcPDE, a Rattlesnake Phosphodiesterase

Neutrophil extracellular traps (NETs) are an important mechanism for defense against pathogens. Their overproduction can be harmful since excessive NET formation promotes inflammation and tissue damage in several diseases. Nucleases are capable to degrade NET on basis of their DNA hydrolysis activit...

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Detalles Bibliográficos
Autores principales: Oliveira, Isadora, Costa, Victor, Veras, Flávio, Ferreira, Isabela, Cunha, Fernando, Cunha, Thiago, Monteiro, Wuelton, Arantes, Eliane, Pucca, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861997/
https://www.ncbi.nlm.nih.gov/pubmed/36668864
http://dx.doi.org/10.3390/toxins15010044