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A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases

Paragonimiasis caused by trematodes belonging to the genus Paragonimus is often accompanied by chronic respiratory symptoms such as cough, the accumulation of sputum, hemoptysis, and chest pain. Prolonged symptoms, including respiratory symptoms, after coronavirus disease 2019 infection (COVID-19) a...

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Autores principales: Sasaki, Jun, Matsuoka, Masanobu, Kinoshita, Takashi, Horii, Takayuki, Tsuneyoshi, Shingo, Murata, Daiki, Takaki, Reiko, Tominaga, Masaki, Tanaka, Mio, Maruyama, Haruhiko, Kawayama, Tomotaka, Hoshino, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862018/
https://www.ncbi.nlm.nih.gov/pubmed/36676761
http://dx.doi.org/10.3390/medicina59010137
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author Sasaki, Jun
Matsuoka, Masanobu
Kinoshita, Takashi
Horii, Takayuki
Tsuneyoshi, Shingo
Murata, Daiki
Takaki, Reiko
Tominaga, Masaki
Tanaka, Mio
Maruyama, Haruhiko
Kawayama, Tomotaka
Hoshino, Tomoaki
author_facet Sasaki, Jun
Matsuoka, Masanobu
Kinoshita, Takashi
Horii, Takayuki
Tsuneyoshi, Shingo
Murata, Daiki
Takaki, Reiko
Tominaga, Masaki
Tanaka, Mio
Maruyama, Haruhiko
Kawayama, Tomotaka
Hoshino, Tomoaki
author_sort Sasaki, Jun
collection PubMed
description Paragonimiasis caused by trematodes belonging to the genus Paragonimus is often accompanied by chronic respiratory symptoms such as cough, the accumulation of sputum, hemoptysis, and chest pain. Prolonged symptoms, including respiratory symptoms, after coronavirus disease 2019 infection (COVID-19) are collectively called post-COVID-19 conditions. Paragonimiasis and COVID-19 may cause similar respiratory symptoms. We encountered five cases of paragonimiasis in patients in Japan for whom diagnoses were delayed due to the initial characterization of the respiratory symptoms as a post-COVID-19 condition. The patients had consumed homemade drunken freshwater crabs together. One to three weeks after consuming the crabs, four of the five patients were diagnosed with probable COVID-19. The major symptoms reported included cough, dyspnea, and chest pain. The major imaging findings were pleural effusion, pneumothorax, and nodular lesions of the lung. All the patients were diagnosed with paragonimiasis based on a serum antibody test and peripheral blood eosinophilia (560–15,610 cells/μL) and were treated successfully with 75 mg/kg/day praziquantel for 3 days. Before diagnosing a post-COVID-19 condition, it is necessary to consider whether other diseases, including paragonimiasis, may explain the symptoms. Further, chest radiographic or blood tests should be performed in patients with persistent respiratory symptoms after being infected with COVID-19 to avoid overlooking the possibility of infection.
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spelling pubmed-98620182023-01-22 A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases Sasaki, Jun Matsuoka, Masanobu Kinoshita, Takashi Horii, Takayuki Tsuneyoshi, Shingo Murata, Daiki Takaki, Reiko Tominaga, Masaki Tanaka, Mio Maruyama, Haruhiko Kawayama, Tomotaka Hoshino, Tomoaki Medicina (Kaunas) Case Report Paragonimiasis caused by trematodes belonging to the genus Paragonimus is often accompanied by chronic respiratory symptoms such as cough, the accumulation of sputum, hemoptysis, and chest pain. Prolonged symptoms, including respiratory symptoms, after coronavirus disease 2019 infection (COVID-19) are collectively called post-COVID-19 conditions. Paragonimiasis and COVID-19 may cause similar respiratory symptoms. We encountered five cases of paragonimiasis in patients in Japan for whom diagnoses were delayed due to the initial characterization of the respiratory symptoms as a post-COVID-19 condition. The patients had consumed homemade drunken freshwater crabs together. One to three weeks after consuming the crabs, four of the five patients were diagnosed with probable COVID-19. The major symptoms reported included cough, dyspnea, and chest pain. The major imaging findings were pleural effusion, pneumothorax, and nodular lesions of the lung. All the patients were diagnosed with paragonimiasis based on a serum antibody test and peripheral blood eosinophilia (560–15,610 cells/μL) and were treated successfully with 75 mg/kg/day praziquantel for 3 days. Before diagnosing a post-COVID-19 condition, it is necessary to consider whether other diseases, including paragonimiasis, may explain the symptoms. Further, chest radiographic or blood tests should be performed in patients with persistent respiratory symptoms after being infected with COVID-19 to avoid overlooking the possibility of infection. MDPI 2023-01-10 /pmc/articles/PMC9862018/ /pubmed/36676761 http://dx.doi.org/10.3390/medicina59010137 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Sasaki, Jun
Matsuoka, Masanobu
Kinoshita, Takashi
Horii, Takayuki
Tsuneyoshi, Shingo
Murata, Daiki
Takaki, Reiko
Tominaga, Masaki
Tanaka, Mio
Maruyama, Haruhiko
Kawayama, Tomotaka
Hoshino, Tomoaki
A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases
title A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases
title_full A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases
title_fullStr A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases
title_full_unstemmed A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases
title_short A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases
title_sort cluster of paragonimiasis with delayed diagnosis due to difficulty distinguishing symptoms from post-covid-19 respiratory symptoms: a report of five cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862018/
https://www.ncbi.nlm.nih.gov/pubmed/36676761
http://dx.doi.org/10.3390/medicina59010137
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