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Improving the Transduction Efficiency and Antitumor Effect of Conditionally Replicative Adenovirus by Application of 6-Cyclohexyl Methyl-β-D-maltoside
As a tumor-targeting oncolytic adenovirus (Ad), conditionally replicating adenovirus (CRAd) can access the cell interior by binding to coxsackievirus-Ad receptors (CARs) and specifically replicate and destroy cancer cells without lethal effects on normal cells. The transduction efficiency of CRAd is...
Autores principales: | Lu, Wenjing, Fang, Yaping, Meng, Xue, Wang, Xiaoli, Liu, Wenbo, Liu, Mengdong, Zhang, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862058/ https://www.ncbi.nlm.nih.gov/pubmed/36677587 http://dx.doi.org/10.3390/molecules28020528 |
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