Skin 11β-hydroxysteroid dehydrogenase type 1 enzyme expression regulates burn wound healing and can be targeted to modify scar characteristics

BACKGROUND: Excessive scarring and fibrosis are the most severe and common complications of burn injury. Prolonged exposure to high levels of glucocorticoids detrimentally impacts on skin, leading to skin thinning and impaired wound healing. Skin can generate active glucocorticoids locally through e...

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Detalles Bibliográficos
Autores principales: Tsai, Kevin H-Y, Shi, Huaikai, Parungao, Roxanne J, Naficy, Sina, Ding, Xiaotong, Ding, Xiaofeng, Hew, Jonathan J, Wang, Xiaosuo, Chrzanowski, Wojciech, Lavery, Gareth G, Li, Zhe, Issler-Fisher, Andrea C, Chen, Jun, Tan, Qian, Maitz, Peter K, Cooper, Mark S, Wang, Yiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862341/
https://www.ncbi.nlm.nih.gov/pubmed/36694861
http://dx.doi.org/10.1093/burnst/tkac052

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