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Identification of Autophagy as a Functional Target Suitable for the Pharmacological Treatment of Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) In Vitro

Mitochondrial membrane protein-associated neurodegeneration (MPAN) is a relentlessly progressive neurodegenerative disorder caused by mutations in the C19orf12 gene. C19orf12 has been implicated in playing a role in lipid metabolism, mitochondrial function, and autophagy, however, the precise functi...

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Detalles Bibliográficos
Autores principales: Zanuttigh, Enrica, Derderian, Kevork, Güra, Miriam A., Geerlof, Arie, Di Meo, Ivano, Cavestro, Chiara, Hempfling, Stefan, Ortiz-Collazos, Stephanie, Mauthe, Mario, Kmieć, Tomasz, Cammarota, Eugenia, Panzeri, Maria Carla, Klopstock, Thomas, Sattler, Michael, Winkelmann, Juliane, Messias, Ana C., Iuso, Arcangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862353/
https://www.ncbi.nlm.nih.gov/pubmed/36678896
http://dx.doi.org/10.3390/pharmaceutics15010267

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