Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Type 1 Diabetes Treated With Leptin

Leptin, a hormone secreted by adipocytes, exhibits therapeutic potential for the treatment of type 1 diabetes (T1D). Protein tyrosine phosphatase 1B (PTP1B) is a key enzyme that negatively regulates leptin receptor signaling. Here, the role of PTP1B in the treatment of T1D was investigated using PTP...

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Detalles Bibliográficos
Autores principales: Ito, Yoshihiro, Sun, Runan, Yagimuma, Hiroshi, Taki, Keigo, Mizoguchi, Akira, Kobayashi, Tomoko, Sugiyama, Mariko, Onoue, Takeshi, Tsunekawa, Taku, Takagi, Hiroshi, Hagiwara, Daisuke, Iwama, Shintaro, Suga, Hidetaka, Konishi, Hiroyuki, Kiyama, Hiroshi, Arima, Hiroshi, Banno, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862406/
https://www.ncbi.nlm.nih.gov/pubmed/35748319
http://dx.doi.org/10.2337/db21-0953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862406/
https://www.ncbi.nlm.nih.gov/pubmed/35748319
http://dx.doi.org/10.2337/db21-0953

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