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Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis

Background: Dietary and environmental factors may influence tolerance acquisition in food protein-induced allergic proctocolitis (FPIAP). This retrospective observational study explored the role of maternal diet during pregnancy and breastfeeding in tolerance acquisition in infantile FPIAP. Methods:...

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Autores principales: Feketea, Gavriela, Lakoumentas, John, Konstantinou, George N., Douladiris, Nikolaos, Papadopoulos, Nikolaos G., Petrodimopoulou, Maria, Tasios, Ioannis, Valianatou, Mina, Vourga, Vasiliki, Vassilopoulou, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862452/
https://www.ncbi.nlm.nih.gov/pubmed/36678296
http://dx.doi.org/10.3390/nu15020425
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author Feketea, Gavriela
Lakoumentas, John
Konstantinou, George N.
Douladiris, Nikolaos
Papadopoulos, Nikolaos G.
Petrodimopoulou, Maria
Tasios, Ioannis
Valianatou, Mina
Vourga, Vasiliki
Vassilopoulou, Emilia
author_facet Feketea, Gavriela
Lakoumentas, John
Konstantinou, George N.
Douladiris, Nikolaos
Papadopoulos, Nikolaos G.
Petrodimopoulou, Maria
Tasios, Ioannis
Valianatou, Mina
Vourga, Vasiliki
Vassilopoulou, Emilia
author_sort Feketea, Gavriela
collection PubMed
description Background: Dietary and environmental factors may influence tolerance acquisition in food protein-induced allergic proctocolitis (FPIAP). This retrospective observational study explored the role of maternal diet during pregnancy and breastfeeding in tolerance acquisition in infantile FPIAP. Methods: Breastfed infants with FPIAP from six diverse regions in Greece were divided into two groups, based on development of tolerance to the trigger food: Group A (n = 43), before, and Group B (n = 53), after, the 6th month of age. Maternal diet during pregnancy and breastfeeding was elicited using the Mediterranean Diet Score Questionnaire and the Mediterranean Oriented Culture Specific Semi-Quantitative Food Frequency Questionnaire. Results: Mean age at diagnosis of FPIAP (1.5 months) and weaning (5.5 months) were the same in both groups. The main trigger was cow’s milk. Group A received infant milk formula earlier than Group B. Group B had a higher incidence of asthma/wheeze, siblings with milk allergy, maternal smoking and rural residence. On multivariate analysis, earlier resolution of FPIAP was associated with higher maternal education and with salt intake and consumption of goat/sheep cheese during pregnancy and olive oil during breastfeeding. Consumption of multivitamins during pregnancy and meat, winter fruits, green vegetables, butter, salt, “ready-to-eat” meals and pastries during breastfeeding were correlated with longer duration of symptoms. Conclusions: Mothers of children with FPIAP to cow’s milk protein can be advised to eat more yogurt, cheese and olive oil during subsequent pregnancies, and avoid multivitamins, grilled food, “ready-to-eat” meals, pastries, meat and alcohol during breastfeeding, to reduce the duration of FPIAP presenting in future infants.
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spelling pubmed-98624522023-01-22 Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis Feketea, Gavriela Lakoumentas, John Konstantinou, George N. Douladiris, Nikolaos Papadopoulos, Nikolaos G. Petrodimopoulou, Maria Tasios, Ioannis Valianatou, Mina Vourga, Vasiliki Vassilopoulou, Emilia Nutrients Article Background: Dietary and environmental factors may influence tolerance acquisition in food protein-induced allergic proctocolitis (FPIAP). This retrospective observational study explored the role of maternal diet during pregnancy and breastfeeding in tolerance acquisition in infantile FPIAP. Methods: Breastfed infants with FPIAP from six diverse regions in Greece were divided into two groups, based on development of tolerance to the trigger food: Group A (n = 43), before, and Group B (n = 53), after, the 6th month of age. Maternal diet during pregnancy and breastfeeding was elicited using the Mediterranean Diet Score Questionnaire and the Mediterranean Oriented Culture Specific Semi-Quantitative Food Frequency Questionnaire. Results: Mean age at diagnosis of FPIAP (1.5 months) and weaning (5.5 months) were the same in both groups. The main trigger was cow’s milk. Group A received infant milk formula earlier than Group B. Group B had a higher incidence of asthma/wheeze, siblings with milk allergy, maternal smoking and rural residence. On multivariate analysis, earlier resolution of FPIAP was associated with higher maternal education and with salt intake and consumption of goat/sheep cheese during pregnancy and olive oil during breastfeeding. Consumption of multivitamins during pregnancy and meat, winter fruits, green vegetables, butter, salt, “ready-to-eat” meals and pastries during breastfeeding were correlated with longer duration of symptoms. Conclusions: Mothers of children with FPIAP to cow’s milk protein can be advised to eat more yogurt, cheese and olive oil during subsequent pregnancies, and avoid multivitamins, grilled food, “ready-to-eat” meals, pastries, meat and alcohol during breastfeeding, to reduce the duration of FPIAP presenting in future infants. MDPI 2023-01-13 /pmc/articles/PMC9862452/ /pubmed/36678296 http://dx.doi.org/10.3390/nu15020425 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Feketea, Gavriela
Lakoumentas, John
Konstantinou, George N.
Douladiris, Nikolaos
Papadopoulos, Nikolaos G.
Petrodimopoulou, Maria
Tasios, Ioannis
Valianatou, Mina
Vourga, Vasiliki
Vassilopoulou, Emilia
Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis
title Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis
title_full Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis
title_fullStr Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis
title_full_unstemmed Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis
title_short Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis
title_sort dietary factors may delay tolerance acquisition in food protein-induced allergic proctocolitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862452/
https://www.ncbi.nlm.nih.gov/pubmed/36678296
http://dx.doi.org/10.3390/nu15020425
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