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Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis
Background: Dietary and environmental factors may influence tolerance acquisition in food protein-induced allergic proctocolitis (FPIAP). This retrospective observational study explored the role of maternal diet during pregnancy and breastfeeding in tolerance acquisition in infantile FPIAP. Methods:...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862452/ https://www.ncbi.nlm.nih.gov/pubmed/36678296 http://dx.doi.org/10.3390/nu15020425 |
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author | Feketea, Gavriela Lakoumentas, John Konstantinou, George N. Douladiris, Nikolaos Papadopoulos, Nikolaos G. Petrodimopoulou, Maria Tasios, Ioannis Valianatou, Mina Vourga, Vasiliki Vassilopoulou, Emilia |
author_facet | Feketea, Gavriela Lakoumentas, John Konstantinou, George N. Douladiris, Nikolaos Papadopoulos, Nikolaos G. Petrodimopoulou, Maria Tasios, Ioannis Valianatou, Mina Vourga, Vasiliki Vassilopoulou, Emilia |
author_sort | Feketea, Gavriela |
collection | PubMed |
description | Background: Dietary and environmental factors may influence tolerance acquisition in food protein-induced allergic proctocolitis (FPIAP). This retrospective observational study explored the role of maternal diet during pregnancy and breastfeeding in tolerance acquisition in infantile FPIAP. Methods: Breastfed infants with FPIAP from six diverse regions in Greece were divided into two groups, based on development of tolerance to the trigger food: Group A (n = 43), before, and Group B (n = 53), after, the 6th month of age. Maternal diet during pregnancy and breastfeeding was elicited using the Mediterranean Diet Score Questionnaire and the Mediterranean Oriented Culture Specific Semi-Quantitative Food Frequency Questionnaire. Results: Mean age at diagnosis of FPIAP (1.5 months) and weaning (5.5 months) were the same in both groups. The main trigger was cow’s milk. Group A received infant milk formula earlier than Group B. Group B had a higher incidence of asthma/wheeze, siblings with milk allergy, maternal smoking and rural residence. On multivariate analysis, earlier resolution of FPIAP was associated with higher maternal education and with salt intake and consumption of goat/sheep cheese during pregnancy and olive oil during breastfeeding. Consumption of multivitamins during pregnancy and meat, winter fruits, green vegetables, butter, salt, “ready-to-eat” meals and pastries during breastfeeding were correlated with longer duration of symptoms. Conclusions: Mothers of children with FPIAP to cow’s milk protein can be advised to eat more yogurt, cheese and olive oil during subsequent pregnancies, and avoid multivitamins, grilled food, “ready-to-eat” meals, pastries, meat and alcohol during breastfeeding, to reduce the duration of FPIAP presenting in future infants. |
format | Online Article Text |
id | pubmed-9862452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98624522023-01-22 Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis Feketea, Gavriela Lakoumentas, John Konstantinou, George N. Douladiris, Nikolaos Papadopoulos, Nikolaos G. Petrodimopoulou, Maria Tasios, Ioannis Valianatou, Mina Vourga, Vasiliki Vassilopoulou, Emilia Nutrients Article Background: Dietary and environmental factors may influence tolerance acquisition in food protein-induced allergic proctocolitis (FPIAP). This retrospective observational study explored the role of maternal diet during pregnancy and breastfeeding in tolerance acquisition in infantile FPIAP. Methods: Breastfed infants with FPIAP from six diverse regions in Greece were divided into two groups, based on development of tolerance to the trigger food: Group A (n = 43), before, and Group B (n = 53), after, the 6th month of age. Maternal diet during pregnancy and breastfeeding was elicited using the Mediterranean Diet Score Questionnaire and the Mediterranean Oriented Culture Specific Semi-Quantitative Food Frequency Questionnaire. Results: Mean age at diagnosis of FPIAP (1.5 months) and weaning (5.5 months) were the same in both groups. The main trigger was cow’s milk. Group A received infant milk formula earlier than Group B. Group B had a higher incidence of asthma/wheeze, siblings with milk allergy, maternal smoking and rural residence. On multivariate analysis, earlier resolution of FPIAP was associated with higher maternal education and with salt intake and consumption of goat/sheep cheese during pregnancy and olive oil during breastfeeding. Consumption of multivitamins during pregnancy and meat, winter fruits, green vegetables, butter, salt, “ready-to-eat” meals and pastries during breastfeeding were correlated with longer duration of symptoms. Conclusions: Mothers of children with FPIAP to cow’s milk protein can be advised to eat more yogurt, cheese and olive oil during subsequent pregnancies, and avoid multivitamins, grilled food, “ready-to-eat” meals, pastries, meat and alcohol during breastfeeding, to reduce the duration of FPIAP presenting in future infants. MDPI 2023-01-13 /pmc/articles/PMC9862452/ /pubmed/36678296 http://dx.doi.org/10.3390/nu15020425 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Feketea, Gavriela Lakoumentas, John Konstantinou, George N. Douladiris, Nikolaos Papadopoulos, Nikolaos G. Petrodimopoulou, Maria Tasios, Ioannis Valianatou, Mina Vourga, Vasiliki Vassilopoulou, Emilia Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis |
title | Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis |
title_full | Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis |
title_fullStr | Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis |
title_full_unstemmed | Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis |
title_short | Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis |
title_sort | dietary factors may delay tolerance acquisition in food protein-induced allergic proctocolitis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862452/ https://www.ncbi.nlm.nih.gov/pubmed/36678296 http://dx.doi.org/10.3390/nu15020425 |
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