Lack of Skeletal Effects in Mice with Targeted Disruptionof Prolyl Hydroxylase Domain 1 (Phd1) Gene Expressed in Chondrocytes

The critical importance of hypoxia-inducible factor (HIF)s in the regulation of endochondral bone formation is now well established. HIF protein levels are closely regulated by the prolyl hydroxylase domain-containing protein (PHD) mediated ubiquitin-proteasomal degradation pathway. Of the three PHD...

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Detalles Bibliográficos
Autores principales: Xing, Weirong, Larkin, Destiney, Pourteymoor, Sheila, Tambunan, William, Gomez, Gustavo A., Liu, Elaine K., Mohan, Subburaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862499/
https://www.ncbi.nlm.nih.gov/pubmed/36676055
http://dx.doi.org/10.3390/life13010106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862499/
https://www.ncbi.nlm.nih.gov/pubmed/36676055
http://dx.doi.org/10.3390/life13010106

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