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Jietacin Derivative Inhibits TNF-α-Mediated Inflammatory Cytokines Production via Suppression of the NF-κB Pathway in Synovial Cells

Synovial inflammation plays a central role in joint destruction and pain in osteoarthritis (OA). The NF-κB pathway plays an important role in the inflammatory process and is activated in OA. A previous study reported that a jietacin derivative (JD), (Z)-2-(8-oxodec-9-yn-1-yl)-1-vinyldiazene 1-oxide,...

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Detalles Bibliográficos
Autores principales:	Muneshige, Kyoko, Inahashi, Yuki, Itakura, Makoto, Iwatsuki, Masato, Hirose, Tomoyasu, Inoue, Gen, Takaso, Masashi, Sunazuka, Toshiaki, Ohashi, Yoshihisa, Ohta, Etsuro, Uchida, Kentaro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862604/ https://www.ncbi.nlm.nih.gov/pubmed/36678502 http://dx.doi.org/10.3390/ph16010005

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