Cargando…

Application of the CDK9 inhibitor FIT-039 for the treatment of KSHV-associated malignancy

Chronic infection with Kaposi’s sarcoma-associated herpes virus (KSHV) in B lymphocytes causes primary effusion lymphoma (PEL), the most aggressive form of KSHV-related cancer, which is resistant to conventional chemotherapy. In this study, we report that the BCBL-1 KSHV(+) PEL cell line does not ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakamoto, Tetsunori, Ajiro, Masahiko, Watanabe, Akira, Matsushima, Shingo, Ueda, Keiji, Hagiwara, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862866/
https://www.ncbi.nlm.nih.gov/pubmed/36670405
http://dx.doi.org/10.1186/s12885-023-10540-y