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Optimization of an Injectable Hydrogel Depot System for the Controlled Release of Retinal-Targeted Hybrid Nanoparticles

A drawback in the development of treatments that can reach the retina is the presence of barriers in the eye that restrain compounds from reaching the target. Intravitreal injections hold promise for retinal delivery, but the natural defenses in the vitreous can rapidly degrade or eliminate therapeu...

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Detalles Bibliográficos
Autores principales: Ottonelli, Ilaria, Bighinati, Andrea, Adani, Elisa, Loll, François, Caraffi, Riccardo, Vandelli, Maria Angela, Boury, Frank, Tosi, Giovanni, Duskey, Jason Thomas, Marigo, Valeria, Ruozi, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862926/
https://www.ncbi.nlm.nih.gov/pubmed/36678654
http://dx.doi.org/10.3390/pharmaceutics15010025