Abcc8 (sulfonylurea receptor-1) knockout mice exhibit reduced axonal injury, cytotoxic edema and cognitive dysfunction vs. wild-type in a cecal ligation and puncture model of sepsis

Sepsis-associated brain injury (SABI) is characterized by an acute deterioration of mental status resulting in cognitive impairment and acquisition of new and persistent functional limitations in sepsis survivors. Previously, we reported that septic mice had evidence of axonal injury, robust microgl...

Descripción completa

Detalles Bibliográficos
Autores principales: Cummings, Jessica, Wu, Yijen L., Dixon, C. Edward, Henchir, Jeremy, Simard, J. Marc, Panigrahy, Ashok, Kochanek, Patrick M., Jha, Ruchira M., Aneja, Rajesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862964/
https://www.ncbi.nlm.nih.gov/pubmed/36681815
http://dx.doi.org/10.1186/s12974-023-02692-2

Ejemplares similares

Ejemplares similares