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Tyrosine Kinase Inhibitors for Glioblastoma Multiforme: Challenges and Opportunities for Drug Delivery

Glioblastoma multiforme (GBM) is an aggressive brain tumor with high mortality rates. Due to its invasiveness, heterogeneity, and incomplete resection, the treatment is very challenging. Targeted therapies such as tyrosine kinase inhibitors (TKIs) have great potential for GBM treatment, however, the...

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Detalles Bibliográficos
Autores principales: Brar, Harpinder K., Jose, Jiney, Wu, Zimei, Sharma, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863099/
https://www.ncbi.nlm.nih.gov/pubmed/36678688
http://dx.doi.org/10.3390/pharmaceutics15010059