CircFBXW7 in patients with T-cell ALL: depletion sustains MYC and NOTCH activation and leukemia cell viability

Circular RNAs (circRNAs) are emerging as new players in leukemogenic mechanisms. In patients with T-cell Acute Lymphoblastic Leukemia (T-ALL), the recent report of a remarkable dysregulation of circRNAs incited further functional investigation. Here we focus on circFBXW7, highly expressed in T-cells...

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Detalles Bibliográficos
Autores principales: Buratin, Alessia, Borin, Cristina, Tretti Parenzan, Caterina, Dal Molin, Anna, Orsi, Silvia, Binatti, Andrea, Simon, Katharina, Paganin, Maddalena, Serafin, Valentina, Gaffo, Enrico, te Kronnie, Geertruij, Van Vlierberghe, Pieter, Bresolin, Silvia, Bortoluzzi, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863195/
https://www.ncbi.nlm.nih.gov/pubmed/36681829
http://dx.doi.org/10.1186/s40164-023-00374-6

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