Genes mcr improve the intestinal fitness of pathogenic E. coli and balance their lifestyle to commensalism

BACKGROUND: The plasmid-mediated resistance gene mcr-1 confers colistin resistance in Escherichia coli and paves the way for the evolution to pan-drug resistance. We investigated the impact of mcr-1 in gut colonization in the absence of antibiotics using isogenic E. coli strains transformed with a p...

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Detalles Bibliográficos
Autores principales: Guillaume, Dalmasso, Racha, Beyrouthy, Sandrine, Brugiroux, Etienne, Ruppé, Laurent, Guillouard, Virginie, Bonnin, Pierre, Saint-Sardos, Amine, Ghozlane, Vincent, Gaumet, Nicolas, Barnich, Julien, Delmas, Richard, Bonnet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863213/
https://www.ncbi.nlm.nih.gov/pubmed/36670449
http://dx.doi.org/10.1186/s40168-022-01457-y

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