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Delayed Leucoencephalopathy as a Complication after Endovascular Therapy of Intracranial Aneurysms—A Case Series

We describe the clinical presentation, radiological findings, treatment and outcomes of three patients with delayed leukoencephalopathy occurring after endovascular treatment (EVT) for cerebral aneurysms—a rare, albeit recurring, complication. The symptoms occurred 6 to 12 months following the EVT o...

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Detalles Bibliográficos
Autores principales: Bakola, Eleni, Papagiannopoulou, Georgia, Palaiodimou, Lina, Lagios, Konstantinos, Archontakis, Eftychios, Theodorou, Aikaterini, Katsanos, Aristeidis H., Triantafyllou, Sokratis, Zouvelou, Vasiliki, Lachanis, Stefanos, Tzanetakos, Dimitrios, Tzartos, John S., Giannopoulos, Sotirios, Tsivgoulis, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863316/
https://www.ncbi.nlm.nih.gov/pubmed/36675425
http://dx.doi.org/10.3390/jcm12020496
Descripción
Sumario:We describe the clinical presentation, radiological findings, treatment and outcomes of three patients with delayed leukoencephalopathy occurring after endovascular treatment (EVT) for cerebral aneurysms—a rare, albeit recurring, complication. The symptoms occurred 6 to 12 months following the EVT of the cerebral aneurysm. Characteristic imaging findings included high-signal changes on T2 images in the white matter without diffusion restriction predominantly at the distribution of the vascular territory of the catheterized arteries, coupled with patchy gadolinium enhancement or low susceptibility weighted imaging (SWI) signals within the white-matter lesions. Steroid pulse therapy is the treatment of choice and promptly improves clinical and imaging findings. Tapering or cessation of steroids may result in clinical and imaging relapses; close- and long-term follow-up for patients presenting this complication is warranted.