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Generation and Characterization of a SARS-CoV-2-Susceptible Mouse Model Using Adeno-Associated Virus (AAV6.2FF)-Mediated Respiratory Delivery of the Human ACE2 Gene

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19) that has caused a pandemic with millions of human infections. There continues to be a pressing need to develop potential therapies and vaccines to inhibit SARS-CoV-2 infectio...

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Detalles Bibliográficos
Autores principales: Tailor, Nikesh, Warner, Bryce M., Griffin, Bryan D., Tierney, Kevin, Moffat, Estella, Frost, Kathy, Vendramelli, Robert, Leung, Anders, Willman, Marnie, Thomas, Sylvia P., Pei, Yanlong, Booth, Stephanie A., Embury-Hyatt, Carissa, Wootton, Sarah K., Kobasa, Darwyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863330/
https://www.ncbi.nlm.nih.gov/pubmed/36680125
http://dx.doi.org/10.3390/v15010085

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