Cargando…

Hooked Up from a Distance: Charting Genome-Wide Long-Range Interaction Maps in Neural Cells Chromatin to Identify Novel Candidate Genes for Neurodevelopmental Disorders

DNA sequence variants (single nucleotide polymorphisms or variants, SNPs/SNVs; copy number variants, CNVs) associated to neurodevelopmental disorders (NDD) and traits often map on putative transcriptional regulatory elements, including, in particular, enhancers. However, the genes controlled by thes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mercurio, Sara, Pozzolini, Giorgia, Baldi, Roberta, Barilà, Sara E., Pitasi, Mattia, Catona, Orazio, D’Aurizio, Romina, Nicolis, Silvia K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863356/ https://www.ncbi.nlm.nih.gov/pubmed/36674677 http://dx.doi.org/10.3390/ijms24021164

Ejemplares similares

Bridging between Mouse and Human Enhancer-Promoter Long-Range Interactions in Neural Stem Cells, to Understand Enhancer Function in Neurodevelopmental Disease
por: D’Aurizio, Romina, et al.
Publicado: (2022)

Detection of Genomic Structural Variants from Next-Generation Sequencing Data
por: Tattini, Lorenzo, et al.
Publicado: (2015)

Biological role of miR-204 and miR-211 in melanoma
por: Vitiello, Marianna, et al.
Publicado: (2018)

Videogaming Frequency and Executive Skills in Young Adults
por: Peracchia, Sara, et al.
Publicado: (2022)

Sox2-Dependent 3D Chromatin Interactomes in Transcription, Neural Stem Cell Proliferation and Neurodevelopmental Diseases
por: Wei, Chia-Lin, et al.
Publicado: (2019)

Recombinant Human Cytomegalovirus (HCMV) RL13 Binds Human Immunoglobulin G Fc
por: Cortese, Mirko, et al.
Publicado: (2012)

Enhanced copy number variants detection from whole-exome sequencing data using EXCAVATOR2
por: D'Aurizio, Romina, et al.
Publicado: (2016)

T3 Critically Affects the Mhrt/Brg1 Axis to Regulate the Cardiac MHC Switch: Role of an Epigenetic Cross-Talk
por: Forini, Francesca, et al.
Publicado: (2020)

Altered Metabolic Profile and Adipocyte Insulin Resistance Mark Severe Liver Fibrosis in Patients with Chronic Liver Disease
por: Gaggini, Melania, et al.
Publicado: (2019)

Editorial: Transcription and chromatin regulators in neurodevelopmental disorders
por: van den Berg, Debbie L. C., et al.
Publicado: (2022)

Discovering the miR-26a-5p Targetome in Prostate Cancer Cells
por: Rizzo, Milena, et al.
Publicado: (2017)

The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells
por: Fazio, Sofia, et al.
Publicado: (2020)

More than just Stem Cells: Functional Roles of the Transcription Factor Sox2 in Differentiated Glia and Neurons
por: Mercurio, Sara, et al.
Publicado: (2019)

Automation, consolidation, and integration in autoimmune diagnostics
por: Tozzoli, Renato, et al.
Publicado: (2015)

Safer Attitude to Risky Decision-Making in Premanifest Huntington’s Disease Subjects
por: D’Aurizio, Giulia, et al.
Publicado: (2019)

Neurodevelopmental Disorders Caused by Defective Chromatin Remodeling: Phenotypic Complexity Is Highlighted by a Review of ATRX Function
por: Timpano, Sara, et al.
Publicado: (2020)

In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes
por: Siena, Emilio, et al.
Publicado: (2016)

Older Adults’ Perceptions of Falls and Falls Prevention: An Interview-Based Study
por: Catona, Danielle
Publicado: (2020)

The Prostate Cancer Cells Resistant to Docetaxel as in vitro Model for Discovering MicroRNAs Predictive of the Onset of Docetaxel Resistance
por: Bascetta, Lorenzo, et al.
Publicado: (2017)

Neurodevelopmental assessment of children with congenital heart diseases using Trivandrum developmental screening chart
por: Uke, Punam, et al.
Publicado: (2023)

FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes
por: Pagin, Miriam, et al.
Publicado: (2021)

Distance stereotesting using vision test charts for intermittent exotropia
por: Nishikawa, Noriko, et al.
Publicado: (2015)

Deconstructing Sox2 Function in Brain Development and Disease
por: Mercurio, Sara, et al.
Publicado: (2022)

The Hook
por: Krevolin, Richard
Publicado: (2015)

Sleep Quality and Psychological Status in a Group of Italian Prisoners
por: D’Aurizio, Giulia, et al.
Publicado: (2020)

Moral Judgement along the Academic Training
por: D’Aurizio, Giulia, et al.
Publicado: (2021)

Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features
por: Li, Dong, et al.
Publicado: (2021)

Chromatin Remodeling Complex NuRD in Neurodevelopment and Neurodevelopmental Disorders
por: Hoffmann, Anke, et al.
Publicado: (2019)

Integrative analysis of differentially expressed genes and miRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemia reperfusion
por: Forini, Francesca, et al.
Publicado: (2018)

Effects of Physical Activity on Cognitive Functioning: The Role of Cognitive Reserve and Active Aging
por: D’Aurizio, Giulia, et al.
Publicado: (2023)

Discovering miRNA Regulatory Networks in Holt–Oram Syndrome Using a Zebrafish Model
por: D’Aurizio, Romina, et al.
Publicado: (2016)

The Hook Worm
Publicado: (1911)

Mesenchymal stem cells-derived vascular smooth muscle cells release abundant levels of osteoprotegerin
por: Corallini, F., et al.
Publicado: (2009)

The emerging role of chromatin remodelers in neurodevelopmental disorders: a developmental perspective
por: Mossink, Britt, et al.
Publicado: (2020)

The FHP01 DDX3X Helicase Inhibitor Exerts Potent Anti-Tumor Activity In Vivo in Breast Cancer Pre-Clinical Models
por: Gherardini, Lisa, et al.
Publicado: (2021)

Charts and LMS Tables of Transfontanellar and Transvertical Ear-to-Ear Distances for Gestational Age
por: Arnold, Nancy, et al.
Publicado: (2022)

Diagnostic accuracy of a new fluoroenzyme immunoassay for the detection of TSH receptor autoantibodies in Graves’ disease
por: Villalta, Danilo, et al.
Publicado: (2018)

Characterization and identification of hidden rare variants in the human genome
por: Magi, Alberto, et al.
Publicado: (2015)

Development and Application of a New T-shaped Internal Trabeculotomy Hook (T-hook)
por: Chihara, Etsuo, et al.
Publicado: (2022)

Efficacy and Safety of Q10 Ubiquinol With Vitamins B and E in Neurodevelopmental Disorders: A Retrospective Chart Review
por: Cucinotta, Francesca, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bnko6pr3a8br0bsgnd44266fog