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Before Direct-Acting Antivirals for Hepatitis C Virus: Evaluation of Core Protein R70Q and L/C91M Substitutions in Chronically Infected Brazilian Patients Unresponsive to IFN and/or RBV

Although chronic hepatitis C has been effectively treated with direct-acting antivirals (DAAs), the use of conventional therapy with peg-interferon (Peg-IFN) or (predominantly) ribavirin (RBV), remains widespread. R70Q/H and L/C91M amino acid substitutions in the hepatitis C virus (HCV) core protein...

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Detalles Bibliográficos
Autores principales: Campos, Letícia Bomfim, de Almeida, Nathália Alves Araújo, de Santana, Catarina Góis, Barbosa, Evorah Nascimento Pereira, Horta, Marco Aurelio Pereira, Amendola Pires, Márcia, Brandão Mello, Carlos Eduardo, de Paula, Vanessa Salete, de Barros, José Júnior França
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863677/
https://www.ncbi.nlm.nih.gov/pubmed/36680226
http://dx.doi.org/10.3390/v15010187

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