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Ketorolac-Loaded PLGA-/PLA-Based Microparticles Stabilized by Hyaluronic Acid: Effects of Formulation Composition and Emulsification Technique on Particle Characteristics and Drug Release Behaviors

This study aimed to develop ketorolac microparticles stabilized by hyaluronic acid based on poly(lactide-co-glycolide) (PLGA), poly(lactide) (PLA), and their blend for further application in osteoarthritis. The polymer blend may provide tailored drug release and improved physicochemical characterist...

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Detalles Bibliográficos
Autores principales: Wongrakpanich, Amaraporn, Khunkitchai, Nichakan, Achayawat, Yanisa, Suksiriworapong, Jiraphong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863719/
https://www.ncbi.nlm.nih.gov/pubmed/36679147
http://dx.doi.org/10.3390/polym15020266