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Nanoparticles of N-Vinylpyrrolidone Amphiphilic Copolymers and Pheophorbide a as Promising Photosensitizers for Photodynamic Therapy: Design, Properties and In Vitro Phototoxic Activity

A series of nanoparticles (NPs) with a hydrodynamic radius from 20 to 100 nm in PBS was developed over the solubilization of hydrophobic dye methyl pheophorbide a (chlorin e(6) derivative) by amphiphilic copolymers of N-vinylpyrrolidone with (di)methacrylates. Photophysical properties and biological...

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Detalles Bibliográficos
Autores principales:	Rybkin, Alexander Yu., Kurmaz, Svetlana V., Urakova, Elizaveta A., Filatova, Natalia V., Sizov, Lev R., Kozlov, Alexey V., Koifman, Mikhail O., Goryachev, Nikolai S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863766/ https://www.ncbi.nlm.nih.gov/pubmed/36678902 http://dx.doi.org/10.3390/pharmaceutics15010273

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