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Bispecific Antibody Format and the Organization of Immunological Synapses in T Cell-Redirecting Strategies for Cancer Immunotherapy
T cell-redirecting strategies have emerged as effective cancer immunotherapy approaches. Bispecific antibodies (bsAbs) are designed to specifically recruit T cells to the tumor microenvironment and induce the assembly of the immunological synapse (IS) between T cells and cancer cells or antigen-pres...
Autores principales: | Carrasco-Padilla, Carlos, Hernaiz-Esteban, Alicia, Álvarez-Vallina, Luis, Aguilar-Sopeña, Oscar, Roda-Navarro, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863865/ https://www.ncbi.nlm.nih.gov/pubmed/36678761 http://dx.doi.org/10.3390/pharmaceutics15010132 |
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