An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2)

A mitochondria-targeted NIR probe based on the FRET mechanism was developed. It shows ultra-large Stokes shifts (460 nm) and emission shifts (285 nm). Furthermore, we also realized the imaging of SO(2) in living SKOV-3 cells, zebrafish and living mice which may be useful for understanding the biolog...

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Detalles Bibliográficos
Autores principales: Cui, Renle, Liu, Caihong, Zhang, Ping, Qin, Kun, Ge, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863934/
https://www.ncbi.nlm.nih.gov/pubmed/36677574
http://dx.doi.org/10.3390/molecules28020515
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author Cui, Renle
Liu, Caihong
Zhang, Ping
Qin, Kun
Ge, Yanqing
author_facet Cui, Renle
Liu, Caihong
Zhang, Ping
Qin, Kun
Ge, Yanqing
author_sort Cui, Renle
collection PubMed
description A mitochondria-targeted NIR probe based on the FRET mechanism was developed. It shows ultra-large Stokes shifts (460 nm) and emission shifts (285 nm). Furthermore, we also realized the imaging of SO(2) in living SKOV-3 cells, zebrafish and living mice which may be useful for understanding the biological roles of SO(2) in mitochondria and in vivo.
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spelling pubmed-98639342023-01-22 An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2) Cui, Renle Liu, Caihong Zhang, Ping Qin, Kun Ge, Yanqing Molecules Article A mitochondria-targeted NIR probe based on the FRET mechanism was developed. It shows ultra-large Stokes shifts (460 nm) and emission shifts (285 nm). Furthermore, we also realized the imaging of SO(2) in living SKOV-3 cells, zebrafish and living mice which may be useful for understanding the biological roles of SO(2) in mitochondria and in vivo. MDPI 2023-01-05 /pmc/articles/PMC9863934/ /pubmed/36677574 http://dx.doi.org/10.3390/molecules28020515 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cui, Renle
Liu, Caihong
Zhang, Ping
Qin, Kun
Ge, Yanqing
An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2)
title An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2)
title_full An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2)
title_fullStr An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2)
title_full_unstemmed An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2)
title_short An Imidazo[1,5-a]pyridine Benzopyrylium-Based NIR Fluorescent Probe with Ultra-Large Stokes Shifts for Monitoring SO(2)
title_sort imidazo[1,5-a]pyridine benzopyrylium-based nir fluorescent probe with ultra-large stokes shifts for monitoring so(2)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863934/
https://www.ncbi.nlm.nih.gov/pubmed/36677574
http://dx.doi.org/10.3390/molecules28020515
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