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Synthesis and Antibacterial Evaluation of Ciprofloxacin Congeners with Spirocyclic Amine Periphery

The synthesis of novel fluoroquinolones, congeners of ciprofloxacin, which was inspired by earlier work on spirocyclic ciprofloxacin, is described. An antibacterial evaluation of the 11 fluoroquinolone compounds synthesized against the ESKAPE panel of pathogens in comparison with ciprofloxacin revea...

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Detalles Bibliográficos
Autores principales: Lukin, Alexei, Komarova, Kristina, Vinogradova, Lyubov, Rogacheva, Elizaveta, Kraeva, Lyudmila, Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863982/
https://www.ncbi.nlm.nih.gov/pubmed/36674469
http://dx.doi.org/10.3390/ijms24020954