Immunization with a Multivalent Listeria monocytogenes Vaccine Leads to a Strong Reduction in Vertical Transmission and Cerebral Parasite Burden in Pregnant and Non-Pregnant Mice Infected with Neospora caninum

Neospora caninum is an apicomplexan parasite that causes abortion and stillbirth in cattle. We employed the pregnant neosporosis mouse model to investigate the efficacy of a modified version of the attenuated Listeria monocytogenes vaccine vector Lm3Dx_NcSAG1, which expresses the major N. caninum su...

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Detalles Bibliográficos
Autores principales: Imhof, Dennis, Pownall, William, Hänggeli, Kai Pascal Alexander, Monney, Camille, Román, Laura Rico-San, Ortega-Mora, Luis-Miguel, Forterre, Franck, Oevermann, Anna, Hemphill, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863997/
https://www.ncbi.nlm.nih.gov/pubmed/36680001
http://dx.doi.org/10.3390/vaccines11010156

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