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Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022

Three epidemic waves of coronavirus disease-19 (COVID-19) occurred in Madagascar from March 2020 to May 2022, with a positivity rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 21% to 33%. Our study aimed to identify the impact of COVID-19 on the epidemiology of seasonal respi...

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Autores principales: Razanajatovo, Norosoa Harline, Randriambolamanantsoa, Tsiry Hasina, Rabarison, Joelinotahiana Hasina, Randrianasolo, Laurence, Ankasitrahana, Miamina Fidy, Ratsimbazafy, Arvé, Raherinandrasana, Antso Hasina, Razafimanjato, Helisoa, Raharinosy, Vololoniaina, Andriamandimby, Soa Fy, Heraud, Jean-Michel, Dussart, Philippe, Lacoste, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864023/
https://www.ncbi.nlm.nih.gov/pubmed/36680053
http://dx.doi.org/10.3390/v15010012
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author Razanajatovo, Norosoa Harline
Randriambolamanantsoa, Tsiry Hasina
Rabarison, Joelinotahiana Hasina
Randrianasolo, Laurence
Ankasitrahana, Miamina Fidy
Ratsimbazafy, Arvé
Raherinandrasana, Antso Hasina
Razafimanjato, Helisoa
Raharinosy, Vololoniaina
Andriamandimby, Soa Fy
Heraud, Jean-Michel
Dussart, Philippe
Lacoste, Vincent
author_facet Razanajatovo, Norosoa Harline
Randriambolamanantsoa, Tsiry Hasina
Rabarison, Joelinotahiana Hasina
Randrianasolo, Laurence
Ankasitrahana, Miamina Fidy
Ratsimbazafy, Arvé
Raherinandrasana, Antso Hasina
Razafimanjato, Helisoa
Raharinosy, Vololoniaina
Andriamandimby, Soa Fy
Heraud, Jean-Michel
Dussart, Philippe
Lacoste, Vincent
author_sort Razanajatovo, Norosoa Harline
collection PubMed
description Three epidemic waves of coronavirus disease-19 (COVID-19) occurred in Madagascar from March 2020 to May 2022, with a positivity rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 21% to 33%. Our study aimed to identify the impact of COVID-19 on the epidemiology of seasonal respiratory viruses (RVs) in Madagascar. We used two different specimen sources (SpS). First, 2987 nasopharyngeal (NP) specimens were randomly selected from symptomatic patients between March 2020 and May 2022 who tested negative for SARS-CoV-2 and were tested for 14 RVs by multiplex real-time PCR. Second, 6297 NP specimens were collected between March 2020 and May 2022 from patients visiting our sentinel sites of the influenza sentinel network. The samples were tested for influenza, respiratory syncytial virus (RSV), and SARS-CoV-2. From SpS-1, 19% (569/2987) of samples tested positive for at least one RV. Rhinovirus (6.3%, 187/2987) was the most frequently detected virus during the first two waves, whereas influenza predominated during the third. From SpS-2, influenza, SARS-CoV-2, and RSV accounted for 5.4%, 24.5%, and 39.4% of the detected viruses, respectively. During the study period, we observed three different RV circulation profiles. Certain viruses circulated sporadically, with increased activity in between waves of SARS-CoV-2. Other viruses continued to circulate regardless of the COVID-19 situation. Certain viruses were severely disrupted by the spread of SARS-CoV-2. Our findings underline the importance and necessity of maintaining an integrated disease surveillance system for the surveillance and monitoring of RVs of public health interest.
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spelling pubmed-98640232023-01-22 Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022 Razanajatovo, Norosoa Harline Randriambolamanantsoa, Tsiry Hasina Rabarison, Joelinotahiana Hasina Randrianasolo, Laurence Ankasitrahana, Miamina Fidy Ratsimbazafy, Arvé Raherinandrasana, Antso Hasina Razafimanjato, Helisoa Raharinosy, Vololoniaina Andriamandimby, Soa Fy Heraud, Jean-Michel Dussart, Philippe Lacoste, Vincent Viruses Article Three epidemic waves of coronavirus disease-19 (COVID-19) occurred in Madagascar from March 2020 to May 2022, with a positivity rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 21% to 33%. Our study aimed to identify the impact of COVID-19 on the epidemiology of seasonal respiratory viruses (RVs) in Madagascar. We used two different specimen sources (SpS). First, 2987 nasopharyngeal (NP) specimens were randomly selected from symptomatic patients between March 2020 and May 2022 who tested negative for SARS-CoV-2 and were tested for 14 RVs by multiplex real-time PCR. Second, 6297 NP specimens were collected between March 2020 and May 2022 from patients visiting our sentinel sites of the influenza sentinel network. The samples were tested for influenza, respiratory syncytial virus (RSV), and SARS-CoV-2. From SpS-1, 19% (569/2987) of samples tested positive for at least one RV. Rhinovirus (6.3%, 187/2987) was the most frequently detected virus during the first two waves, whereas influenza predominated during the third. From SpS-2, influenza, SARS-CoV-2, and RSV accounted for 5.4%, 24.5%, and 39.4% of the detected viruses, respectively. During the study period, we observed three different RV circulation profiles. Certain viruses circulated sporadically, with increased activity in between waves of SARS-CoV-2. Other viruses continued to circulate regardless of the COVID-19 situation. Certain viruses were severely disrupted by the spread of SARS-CoV-2. Our findings underline the importance and necessity of maintaining an integrated disease surveillance system for the surveillance and monitoring of RVs of public health interest. MDPI 2022-12-20 /pmc/articles/PMC9864023/ /pubmed/36680053 http://dx.doi.org/10.3390/v15010012 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Razanajatovo, Norosoa Harline
Randriambolamanantsoa, Tsiry Hasina
Rabarison, Joelinotahiana Hasina
Randrianasolo, Laurence
Ankasitrahana, Miamina Fidy
Ratsimbazafy, Arvé
Raherinandrasana, Antso Hasina
Razafimanjato, Helisoa
Raharinosy, Vololoniaina
Andriamandimby, Soa Fy
Heraud, Jean-Michel
Dussart, Philippe
Lacoste, Vincent
Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022
title Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022
title_full Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022
title_fullStr Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022
title_full_unstemmed Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022
title_short Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022
title_sort epidemiological patterns of seasonal respiratory viruses during the covid-19 pandemic in madagascar, march 2020–may 2022
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864023/
https://www.ncbi.nlm.nih.gov/pubmed/36680053
http://dx.doi.org/10.3390/v15010012
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