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In Vivo Safety and Efficacy of Chalcone-Loaded Microparticles with Modified Polymeric Matrix against Cutaneous Leishmaniasis
Current chemotherapy of cutaneous leishmaniasis (CL) is based on repeated systemic or intralesional administration of drugs that often cause severe toxicity. Previously, we demonstrated the therapeutic potential of biodegradable poly(lactic-co-glycolic acid) (PLGA) microparticles (MPs) loaded with 8...
Autores principales: | Sousa-Batista, Ariane de J., Arruda-Costa, Natalia, Pacienza-Lima, Wallace, Carvalho-Gondim, Felipe, Santos, Rosiane F., Da-Silva, Silvia A. G., Ré, Maria Inês, Rossi-Bergmann, Bartira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864040/ https://www.ncbi.nlm.nih.gov/pubmed/36678680 http://dx.doi.org/10.3390/pharmaceutics15010051 |
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