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Inhibition of Voltage-Gated Na(+) Currents Exerted by KB-R7943 (2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea), an Inhibitor of Na(+)-Ca(2+) Exchanging Process
KB-R7943, an isothiourea derivative, has been recognized as an inhibitor in the reverse mode of the Na(+)-Ca(2+) exchanging process. This compound was demonstrated to prevent intracellular Na(+)-dependent Ca(2+) uptake in intact cells; however, it is much less effective at preventing extracellular N...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864174/ https://www.ncbi.nlm.nih.gov/pubmed/36675319 http://dx.doi.org/10.3390/ijms24021805 |