Dual Target of EGFR and mTOR Suppresses Triple-Negative Breast Cancer Cell Growth by Regulating the Phosphorylation of mTOR Downstream Proteins

OBJECTIVE: To detect the activation of the EGFR and mTOR signaling pathways in the triple negative breast cancer cell line MDA-MB-468 and investigate the inhibitory effect of gefitinib, an epidermal growth factor receptor inhibitor, and everolimus, a target protein inhibitor of rapamycin, on triple...

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Detalles Bibliográficos
Autores principales: Ma, Jing, Dong, Chao, Cao, Yan-Zhen, Ma, Bin-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864233/
https://www.ncbi.nlm.nih.gov/pubmed/36691572
http://dx.doi.org/10.2147/BCTT.S390017

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