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Phenylsulfonimide PPARα Antagonists Enhance Nrf2 Activation and Promote Oxidative Stress-Induced Apoptosis/Pyroptosis in MCF7 Breast Cancer Cells

The NF-E2-related factor 2 transcription factor (Nrf2) orchestrates the basal and stress-inducible activation of a vast array of antioxidant genes. A high amount of reactive oxygen species (ROS) promotes carcinogenesis in cells with defective redox-sensitive signaling factors such as Nrf2. In breast...

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Detalles Bibliográficos
Autores principales:	Gallorini, Marialucia, Di Valerio, Valentina, Bruno, Isabella, Carradori, Simone, Amoroso, Rosa, Cataldi, Amelia, Ammazzalorso, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864319/ https://www.ncbi.nlm.nih.gov/pubmed/36674831 http://dx.doi.org/10.3390/ijms24021316

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