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Targeting IRAK4 with Emavusertib in Lymphoma Models with Secondary Resistance to PI3K and BTK Inhibitors
Inhibitors of phosphatidylinositol 3-kinase (PI3K) and Bruton tyrosine kinase (BTK) represent a recognized option for the treatment of patients affected by indolent B cell lymphomas. However, small molecules as single agents show limited success in their ability in inducing complete responses, with...
Autores principales: | Guidetti, Francesca, Arribas, Alberto J., Sartori, Giulio, Spriano, Filippo, Barnabei, Laura, Tarantelli, Chiara, Von Roemeling, Reinhard, Martinez, Elizabeth, Zucca, Emanuele, Bertoni, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864368/ https://www.ncbi.nlm.nih.gov/pubmed/36675328 http://dx.doi.org/10.3390/jcm12020399 |
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