Cargando…

Newly Synthesized Creatine Derivatives as Potential Neuroprotective and Antioxidant Agents on In Vitro Models of Parkinson’s Disease

Oxidative stress is one of the key factors responsible for many diseases–neurodegenerative (Parkinson and Alzheimer) diseases, diabetes, atherosclerosis, etc. Creatine, a natural amino acid derivative, is capable of exerting mild, direct antioxidant activity in cultured mammalian cells acutely injur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kostadinova, Ivanka, Kondeva-Burdina, Magdalena, Marinov, Lyubomir, Vezenkov, Lubomir L., Simeonova, Rumyana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864416/ https://www.ncbi.nlm.nih.gov/pubmed/36676090 http://dx.doi.org/10.3390/life13010139

Ejemplares similares

Some In Vitro/In Vivo Chemically-Induced Experimental Models of Liver Oxidative Stress in Rats
por: Simeonova, Rumyana, et al.
Publicado: (2014)

Selective Nitric Oxide Synthase Inhibitor 7-Nitroindazole Protects against Cocaine-Induced Oxidative Stress in Rat Brain
por: Vitcheva, Vessela, et al.
Publicado: (2015)

Hepatoprotective and Antioxidant Effects of Saponarin, Isolated from Gypsophila trichotoma Wend. on Paracetamol-Induced Liver Damage in Rats
por: Simeonova, Rumyana, et al.
Publicado: (2013)

Preliminary in vitro evaluation of neuroprotective and monoamine oxidase type B inhibitory effects of newly synthesized 8-aminocaffeines
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2019)

Antioxidant and Hepatoprotective Potential of Echinops ritro L. Extracts on Induced Oxidative Stress In Vitro/In Vivo
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2023)

In Silico Evaluation and In Vitro Determination of Neuroprotective and MAO-B Inhibitory Effects of Pyrrole-Based Hydrazones: A Therapeutic Approach to Parkinson’s Disease
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2022)

Cycloartane Saponins from Astragalus glycyphyllos and Their In Vitro Neuroprotective, Antioxidant, and hMAO-B-Inhibiting Effects
por: Stambolov, Ivan, et al.
Publicado: (2023)

Study on the Neuroprotective, Radical-Scavenging and MAO-B Inhibiting Properties of New Benzimidazole Arylhydrazones as Potential Multi-Target Drugs for the Treatment of Parkinson’s Disease
por: Anastassova, Neda, et al.
Publicado: (2022)

Cytoprotective and antioxidant effects of phenolic compounds from Haberlea rhodopensis Friv. (Gesneriaceae)
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2013)

In Vitro/In Vivo Hepatoprotective and Antioxidant Effects of Defatted Extract and a Phenolic Fraction Obtained from Phlomis Tuberosa
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2023)

Quantitative Structure–Neurotoxicity Assessment and In Vitro Evaluation of Neuroprotective and MAO-B Inhibitory Activities of Series N′-substituted 3-(1,3,7-trimethyl-xanthin-8-ylthio)propanehydrazides
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2022)

Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents: monoamine oxidase-B inhibition, neuroprotection and oxidative stress modulation
por: Anastassova, Neda, et al.
Publicado: (2021)

Effects of rhamnocitrin 4-β-D-galactopyranoside, isolated from Astragalus hamosus on toxicity models in vitro
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2014)

Flavonoid profiles of three Bupleurum species and in vitro hepatoprotective of activity Bupleurum flavum Forsk.
por: Gevrenova, Reneta, et al.
Publicado: (2015)

Creatine salts provide neuroprotection even after partial impairment of the creatine transporter
por: Adriano, E., et al.
Publicado: (2017)

Development of Hyphenated Techniques and Network Identification Approaches for Biotransformational Evaluation of Promising Antitubercular N-pyrrolyl hydrazide-hydrazone in Isolated Rat Hepatocytes
por: Mateeva, Alexandrina, et al.
Publicado: (2023)

Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications
por: Kichukova, Diana, et al.
Publicado: (2022)

Effects of Aronia melanocarpa Fruit Juice on Isolated Rat Hepatocytes
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2015)

Antioxidant and Antitumor Activities of Newly Synthesized Hesperetin Derivatives
por: Zhong, Guanlin, et al.
Publicado: (2022)

Ex Vivo Antioxidant and Cholinesterase Inhibiting Effects of a Novel Galantamine–Curcumin Hybrid on Scopolamine-Induced Neurotoxicity in Mice
por: Simeonova, Rumyana, et al.
Publicado: (2022)

Both Creatine and Its Product Phosphocreatine Reduce Oxidative Stress and Afford Neuroprotection in an In Vitro Parkinson’s Model
por: Cunha, Mauricio Peña, et al.
Publicado: (2014)

The Promise of Neuroprotective Agents in Parkinson’s Disease
por: Seidl, Stacey E., et al.
Publicado: (2011)

Simultaneous analysis of water-soluble and fat-soluble vitamins through RP-HPLC/DAD in food supplements and brewer’s yeast
por: Mateeva, Alexandrina, et al.
Publicado: (2022)

Developmental changes in the expression of creatine synthesizing enzymes and creatine transporter in a precocial rodent, the spiny mouse
por: Ireland, Zoe, et al.
Publicado: (2009)

Assessment of surgical sutures POLYMED(®) by intracutaneous irritation test in rabbits
por: Simeonova, Rumyana, et al.
Publicado: (2013)

Nutraceutical Antioxidants as Novel Neuroprotective Agents
por: Kelsey, Natalie A., et al.
Publicado: (2010)

Synthesis, DFT Study, and In Vitro Evaluation of Antioxidant Properties and Cytotoxic and Cytoprotective Effects of New Hydrazones on SH-SY5Y Neuroblastoma Cell Lines
por: Tzankova, Diana, et al.
Publicado: (2023)

Erratum: The promise of neuroprotective agents in Parkinson's disease
por: Seidl, Stacey E., et al.
Publicado: (2013)

A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders
por: Simeonova, Rumyana, et al.
Publicado: (2021)

Effect of cytisine on some brain and hepatic biochemical parameters in spontaneously hypertensive rats
por: Simeonova, Rumyana, et al.
Publicado: (2010)

Neuroprotection by immunomodulatory agents in animal models of Parkinson’s disease
por: Martinez, Bridget, et al.
Publicado: (2018)

Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
por: Nadeem, Muhammad Shahid, et al.
Publicado: (2021)

Recent Advances in Anti-Tuberculosis Drug Discovery Based on Hydrazide–Hydrazone and Thiadiazole Derivatives Targeting InhA
por: Teneva, Yoanna, et al.
Publicado: (2023)

Design, synthesis and antiproliferative screening of newly synthesized acrylate derivatives as potential anticancer agents
por: Alshaya, Dalal Sulaiman, et al.
Publicado: (2023)

Novel Hydroxytyrosol-Donepezil Hybrids as Potential Antioxidant and Neuroprotective Agents
por: Costanzo, Paola, et al.
Publicado: (2021)

Synthesis and biological evaluation of capsaicin analogues as antioxidant and neuroprotective agents
por: Xie, Mao, et al.
Publicado: (2023)

The interactions of model cationic drug with newly synthesized starch derivatives
por: Kobryń, Justyna, et al.
Publicado: (2023)

The Phytochemical Profiling, In Vitro Antioxidant, and Hepatoprotective Activity of Prenanthes purpurea L. and Caffeoylquinic Acids in Diclofenac-Induced Hepatotoxicity on HEP-G2 Cells
por: Mihaylova, Rositsa, et al.
Publicado: (2023)

Recent Advances on the Neuroprotective Potential of Antioxidants in Experimental Models of Parkinson’s Disease
por: Koppula, Sushruta, et al.
Publicado: (2012)

New Indole-3-Propionic Acid and 5-Methoxy-Indole Carboxylic Acid Derived Hydrazone Hybrids as Multifunctional Neuroprotectors
por: Anastassova, Neda, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_eeeaf0luq0git22f5m975ekjum