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Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis

ANCA-associated vasculitis (AAV) is intricately linked with infections. Toll-like receptors (TLR) provide a potential link between infection and anti-myeloperoxidase (MPO) autoimmunity. TLR9 ligation has been shown to promote anti-MPO autoimmunity and glomerular vasculitis in murine MPO-AAV. This st...

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Detalles Bibliográficos
Autores principales:	Ford, Sharon L., O’Sullivan, Kim M., Kitching, A. Richard, Holdsworth, Stephen R., Gan, Poh Yi, Summers, Shaun A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864438/ https://www.ncbi.nlm.nih.gov/pubmed/36674855 http://dx.doi.org/10.3390/ijms24021339

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