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Iron Acquisition Proteins of Pseudomonas aeruginosa as Potential Vaccine Targets: In Silico Analysis and In Vivo Evaluation of Protective Efficacy of the Hemophore HasAp

Background: Pseudomonas aeruginosa (PA) is a Gram-negative pathogen responsible for fatal nosocomial infections worldwide. Iron is essential for Gram-negative bacteria to establish an infection. Therefore, iron acquisition proteins (IAPs) of bacteria are attractive vaccine targets. Methodology: A “R...

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Detalles Bibliográficos
Autores principales: Hamad, Abdelrahman S., Edward, Eva A., Sheta, Eman, Aboushleib, Hamida M., Bahey-El-Din, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864456/
https://www.ncbi.nlm.nih.gov/pubmed/36679873
http://dx.doi.org/10.3390/vaccines11010028

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