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Safety of Rifampicin at High Dose for Difficult-to-Treat Tuberculosis: Protocol for RIAlta Phase 2b/c Trial
Previous clinical trials for drug-susceptible tuberculosis (DS-TB) have shown that first-line treatment with doses of rifampicin up to 40 mg/kg are safe and increase the early treatment response for young adults with pulmonary tuberculosis. This may lead to a shorter treatment duration for those per...
Autores principales: | Espinosa-Pereiro, Juan, Ghimire, Samiksha, Sturkenboom, Marieke G. G., Alffenaar, Jan-Willem C., Tavares, Margarida, Aguirre, Sarita, Battaglia, Arturo, Molinas, Gladys, Tórtola, Teresa, Akkerman, Onno W., Sanchez-Montalva, Adrian, Magis-Escurra, Cecile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864493/ https://www.ncbi.nlm.nih.gov/pubmed/36678638 http://dx.doi.org/10.3390/pharmaceutics15010009 |
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