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Measurement of Autophagy Activity Reveals Time-Dependent, Bacteria-Specific Turnover during Mycobacterium tuberculosis Infection

The intracellular pathogen, Mycobacterium tuberculosis (M. tb) uses various mechanisms to evade its killing. One of such is phagosomal damage and cytosolic translocation which is then targeted by the host’s bactericidal autophagy pathway. It is suggested that cytosolic translocation of M. tb is time...

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Detalles Bibliográficos
Autores principales: Okugbeni, Naomi, du Toit, André, Cole-Holman, Victoria, Johnson, Glynis, Loos, Ben, Kinnear, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864524/
https://www.ncbi.nlm.nih.gov/pubmed/36678372
http://dx.doi.org/10.3390/pathogens12010024

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