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Role of Myeloid Cell-Specific TLR9 in Mitochondrial DNA-Induced Lung Inflammation in Mice

Mitochondrial dysfunction is common in various pathological conditions including obesity. Release of mitochondrial DNA (mtDNA) during mitochondrial dysfunction has been shown to play a role in driving the pro-inflammatory response in leukocytes including macrophages. However, the mechanisms by which...

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Detalles Bibliográficos
Autores principales: Dimasuay, Kris Genelyn, Berg, Bruce, Schaunaman, Niccolette, Chu, Hong Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864555/
https://www.ncbi.nlm.nih.gov/pubmed/36674451
http://dx.doi.org/10.3390/ijms24020939