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SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors

A growing body of preclinical evidence recognized selective sirtuin 2 (SIRT2) inhibitors as novel therapeutics for treatment of age-related diseases. However, none of the SIRT2 inhibitors have reached clinical trials yet. Transformative potential of machine learning (ML) in early stages of drug disc...

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Detalles Bibliográficos
Autores principales: Djokovic, Nemanja, Rahnasto-Rilla, Minna, Lougiakis, Nikolaos, Lahtela-Kakkonen, Maija, Nikolic, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864763/
https://www.ncbi.nlm.nih.gov/pubmed/36678624
http://dx.doi.org/10.3390/ph16010127